I’ve never really noticed much of an effect from probiotics. About a year ago I started to take them in higher dosages and I started noticing some benefits for the gut, but not much else.
As I study the immune system more and these individual probiotic species that I’m ingesting, I started thinking that there is a gap between what I’m reading and what I’m experiencing.
Probiotics are good, but reading the research, I would’ve expected more from it.
So I thought it’s time to experiment with probiotics the same way I do with other substances: take more until I feel an acute effect.
The reason I wanted to do this was because I was getting some gas from my experiments with NAG, Sialic acid and Mannose. I also couldn’t take NAC because I’d get gas from that, too.
I also wanted to do some experiments for inducing oral tolerance more.
My First Two Experiments: Ingesting 280 Billion Microbes
So, at first I decided to do a little experiment and ingest 280 billion probiotic bacteria in one shot, containing 15 different strains. This is equivalent to two bottles of your run of the mill probiotics.
My result? I felt high and blissful. The effect was strong.
I also got a bit itchy and red in some places, but nothing serious.
My results were confounded by taking 40X the dosage of Mannose earlier. Normally they come in pills of 500mg. I took 20g yesterday. I also took a lot of Black Cumin Seed Oil.
I did the experiment again and got a similar effect, but I still took a lot of Black Cumin Seed Oil.
My Third Experiment: Ingesting 660 Billion Bacteria
In the first 2 experiments, I took most of the bottle of a probiotic with a smaller count of 5 billion bacteria. There were also some confounding variables.
I waited maybe a month between this and the last two experiments.
This time I took 10 capsules of a probiotic with 66 billion bacteria in each pill. This equals 660 billion bacteria. I made sure there was no confounding variables this time.
To take the amount that I took, you’d have to take 132 pills of your standard 5 billion species probiotic. Many probiotics have only 1 billion bacteria, which means you’d have to take 660 pills of this to get the dosage I got.
I also had some gas from over-consuming these dried Blueberries (a pound) and too much brussel sprouts ( a pound). Could also be because I was experimenting with lots of chocolate in the preceding days, which makes my gut act up.
Anyway, the effect was the same as the first two times, but stronger. It was incredibly relaxing and made me feel really good. It’s an incredible anti-depressant.
I experienced cognitive sensations the next day was pretty powerful. Any stronger and it would’ve turned into a headache.
There was the same sensations in my skin as well. I felt a bit of intestinal discomfort for an hour, but this went away.
In all three experiments, all gas went away when challenged with gas promoting supplements and food.
Honestly, most of the effects took place while I was sleeping because it hit me strongly an hour before bed and I felt it strongly still as I woke up and the next day. My sleep was really good.
Also, my appetite was noticeably suppressed.
While it’s relaxing, it’s also wakeful-promoting.
I also seem to tolerate lectins better (not as fatigued after).
660 billion bacteria is too much for me. I don’t know what the long term effects of this is. I’d rather take 1 pill 2X a day chronically, which I would consider a minimum effective dosage.
Well, it was important that I knew it was working and how.
My Experiment With Prescript Assist
I also mega-dosed with prescript assist (15 capsules) and felt a similar effect. It was slightly different, but not enough to be able to describe.
The takeaway is that you need to hit things hard. Don’t think you will be cured by taking 1 small pill of 5 billion probiotics.
I see people that can’t function at all in the day and they’re being timid. If your body is broken, baby steps won’t fix you. They’re better than nothing, but bold (but safe) actions need to be taken.
I currently have no health problems I’m still hitting things hard (more to see the effects).
If you have gut problems, then slowly ramp up your probiotic usage until you get side effects or the desired effect.
Don’t be timid.
Potential Side Effects
This approach isn’t risk free, but if done in a careful way, it’s relatively safe.
The only potential problem I see is imbalancing your immune system more. So make sure you take probiotics that balance your immune system the way you want it to. This is why you should start small.
For myself, I just wasn’t concerned about my immune system becoming imbalanced. But everyone is different.
I had a client who felt more than a half of a capsule of 5 billion species was too strong for her. She reacted to every supplement she took.
If you’re in a precarious state, then your risks are greater, but your potential rewards are also greater.
Overall, though, probiotics are pretty safe.
I’m going to experiment in the future with creating tolerance to eggs. To do this, I will take megadoses of probiotics – probably the same dosage of 660 billion bacteria together with my eggs. I will make sure to add Cod liver as well.
A commenter has pointed out there are more bacteria per a capsule in VSL-3. However, there are only 8 strains versus 14 for the swanson version. When you compare the prices, the Swanson brand comes out to be cheaper.
They sell an alternative product of 450 billion bacteria in a sachet. I may try this out in the future, but I’ve gotten good results from the Swanson one. A benefit of VSL is that it’s always cool, which preserves the bacteria better.