“It is not that I’m so smart. But I stay with the questions much longer.”
― Albert Einstein
Supplements For Brain Fog
Before you proceed, make sure you read: Brain Fog Treatment, Part 1: Diet and Lifestyle
If the dosing information isn’t written, it means that you should follow the standard instructions on the label.
Brain fog is almost always caused by inflammation, immune imbalance, and mitochondrial dysfunction.
Reverse Mitochondrial Breakdown
These have all been tried and tested by me. I’ve tried every mitochondrial enhancer on the market and these are the best. They work.
These dosages are meant to be taken individually. If you’re stacking, then cut everything in half.
- PQQ 
- Lactate: Kombucha [2, 3]. Not for Th2 dominant.
- Nicotinamide Riboside [4, 5]
- C60 [6, 7]
- Oxaloacetate [8, 9]
- Gotu Kola 
- Gynostemma 
- Lipoic Acid
- Hydroxytyrosol 
Reduce Th1 Dominance
- Curcumin 
- EGCG 
- Lactic acid 
- Boswellia 
- Theaflavins [17, 18]
- NAG 
- Sialic Acid
- Fisetin 
- Black Cumin Seed Oil 
- Pregnenolone (22)
- Hops (xanthohumol) 
Reduce Th2 Dominance
I realize many people just want the bottom line. Here it is:
- Sun/UVB  – UVB decreases IFNy in Th1 dominance but increases it in Th2 dominance. So it’s balancing. It also decreases IgE responses. UVA in the sun also decreases Th2 dominance .
- Probiotics – Decreases Th2: L. Reuteri  (probiotic), L. Plantarum  (probiotic), L. salivarius  (probiotic), L. lactis  (probiotic) – Increases Th1: S. boulardii? , L. sporogenes, L. acidophilus , L. casei , L. rhamnosus GG , L. paracasei , L. salivarius , B. Longum , L. Brevis , L. fermentum 
- NAC/Glutathione sufficiency decreases Th2  and increases Th1 . 1 cap 2X a day with breakfast and lunch.
- Licorice – 18/β-glycyrrhetinic acid+LicoA [38, 39]. Glycyrrhizin increases IFNy and decreases the Th2 response [40, 41].
- Gynostemma . This is a Th1 immune stimulant and reduces allergies. Gynostemma is recommended also because it’s a powerful mitochondrial enhancer.
- Ginger or juice the root [43, 44]. Recommended because it has anecdotal support in addition to the research, but also because you can get it everywhere, it has a long history of use and for its multitude of other benefits. My mother who is Th2 dominant finds this very helpful for her allergies.
- Reishi . Recommended because it’s a medicinal mushroom, which has unique health properties. It works in many ways. It’s a favorite substance of mine but I don’t take anymore so that I don’t stimulate my immune system.
- Tinospora . This has a clinical trial backing it, with some anecdotal support.
- Quercetin 
The Most Effective Devices for Treating Brain Fog
These are all very important.
- Selenium or a brazil nut
- Citicoline or lecithin
Take note that I am limited in that this is a general protocol and not tailored to an individual.
For example, people with candida experience brain fog, but this protocol isn’t meant for them. Candida is caused in part by lower immunity instead of increased immunity. Candida sufferers should not take NAG since it’s used by candida to grow and become more virulent . Mannose can also cause candida to grow  and probably sialic acid as well. However, only a small percentage of brain fog cases are from candida in my experience and the effects are different than other types of brain fog.
The dosage that you should take depends on your case and other things you are taking.
Each case is different. With no knowledge of the individual, this is the best I can recommend. You’ll just need to experiment more with what works for you.
Also, keep in mind that brain fog, like every other chronic disease, has multiple causes and is resistant to treatment by a single intervention.
This is why it is so difficult to cure depression, anxiety, cancer, and any other chronic condition.
Once a disease takes hold, it’s the norm and while interventions can temporarily fix these problems, the body has a knack to adapt to its former diseased state.
Focusing on a single approach will not work, but it can help a little. Chronic issues need to be addressed from all angles and then once the body develops a new homeostasis, adjustments can be made. The more severe your brain fog is the more of these tools you’ll need to use.
It can take a few months for the full effect to take root, but improvements will be felt along the way.
If you take everything in one shot it will probably be too dramatic, so I encourage you to introduce one supplement at a time.
If the effects are too strong, then simply reduce the dosage or reduce the total supplement load. This is an important concept. Also, after you realize the brain fog is disappearing you can start to withdraw some of the treatments.
Don’t allow this long and comprehensive list to scare you into inertia or think some of the treatments aren’t significant.
If you can only try some, then it’s better than nothing.
Additionally, don’t use supplements as a crutch and neglect other important aspects of this regimen.
Additional Supplements for Infection Derived Brain Fog
People who suddenly started experiencing brain fog after an infection must use additional tools to fight off the infection. The same mechanisms are at play and therefore the regime doesn’t change, but the root cause is different and therefore some additions are required.
Possibly some pharmaceuticals should be added if this is the case.
The regimen already includes many antimicrobials and immune boosters, which would go a long way.
Brain Fog Caused by Heavy Metals
If your brain fog is caused by oxidative stress from heavy metals, then I would suggest Modified Citrus Pectin and a lot of kombucha.
MCP binds to only the harmful heavy metals in the body while leaving alone the beneficial minerals.
Kombucha is loaded with gluconate, which binds to heavy metals.
If you have issues with mercury in particular, then add in Stabilized R-Lipoic Acid. RLA is very good at excreting mercury within your cells.
Video: How The Mitochondria Makes Energy
Tools and Materials to Help You With Brain Fog
Because it’s such a complex, multifactorial issue, you are more likely to succeed trying to fix brain fog with cumulative effects of multiple interventions. However, I notice my clients who have brain fog are usually not very good at telling if something helps their brain fog subtly. Tools like Brain Gauge can help you quantify the nuanced effect of each thing you try for brain fog so that you know you are going in the right direction. You can read about Brain Gauge here and get yours here.
Want to learn more about Th1/Th2 dominance and the latest science, check out our All About Inflammation mini course.
This section contains sponsored links, which means that we may receive a small percentage of profit from your purchase, while the price remains the same to you. The proceeds from your purchase support our research and work. Thank you for your support.