Evidence Based
4.8 /5
8

Hormesis – The Most Effective Tool for Enhancement

Written by Joe Cohen, BS | Last updated:

SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. We believe that the most accurate information is found directly in the scientific source.

We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic.

Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.

Our science team goes through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again.

Our goal is to not have a single piece of inaccurate information on this website. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [email protected]

Note that each number in parentheses [1, 2, 3, etc.] is a clickable link to peer-reviewed scientific studies. A plus sign next to the number “[1+, 2+, etc...]” means that the information is found within the full scientific study rather than the abstract.

hormesis-and-antioxidants2

The Spirit of Hormesis

Let’s face it. Most “nootropics” don’t work well for youngish healthy individuals, at least in my experience. As my health problems disappeared, I naturally started to search for the best tools for enhancement and I realized everything that was highly effective fell into 2 categories. They either corrected a deficiency or worked by hormesis.

Hormesis is the best method for enhancement for people who are already healthy. Hormesis is the concept of introducing an acute stress to the body, in which case the body will have a reaction that will prep it for future stressors that are even stronger. By being prepped, the body can be shifted into a state of higher performance.

Vaccines work in this manner. You introduce a tiny dose of a pathogen and the body responds with developing immunity to an even bigger onslaught of that pathogen. When you introduce small stressors, the body will super-compensate and become stronger.

Exercise mainly works by hormesis as well, which is why it’s an effective enhancement tool for people who are already very healthy.

The American ethos, though, has a hard time digesting this concept and using it properly. We like the concept of becoming stronger but we lack the culture of moderation and the wisdom that less is more. We view hormesis as what doesn’t kill you makes you stronger.

In reality, what doesn’t harm you too much makes you stronger. We like to take things to the extreme, though. If something is good we’ll do more of it. Exercise is healthy? Great. Time to run marathons.

The dose used in hormesis must be carefully applied according to the individual’s initial condition. For example, someone who hasn’t exercised in years shouldn’t suddenly engage in exhaustive exercise. In the same vein, someone with a ‘leaky gut’ should not be exercising exhaustively or drinking alcohol because these things exacerbate such a condition. With hormesis, the dose is key. A little is great and a lot is terrible.

The conditional nature of hormesis adds complexity and naturally, humans don’t like this because we tend to view the world in a binary fashion, where things are either good or bad. If it’s good, we like it and if it’s not we don’t. A nuanced approach is missing here, where the answer isn’t “yes” or “no” but rather “it depends.”

The human body is a complex system that requires nuance more than less complex systems. By categorizing things clearly, nuance gets lost in the jungle of labels. By not truly accepting this idea that less is more, many bloggers and people tend to take things too far. If we don’t use hormesis properly it can cause more harm than good.

Examples of Hormesis in Health

  • Cold Showers
  • Fasting
  • Protein Restriction
  • Calorie Restriction
  • Sun
  • Interval exercise – sprints, weight lifting
  • Using an oxygen tank- or breathing exercises
  • Yoga
  • Psychological stress
  • Dual N-Back
  • Meditation – has some aspects of it
  • Alcohol
  • Getting glycogen depletes
  • Vaccines
  • Herbal supplements – Adaptogens, Curcumin, Resveratrol, Berberine, Gynostemma, Grapeseed extract, etc.
  • Vegetables, plant-based foods – plant toxins
  • Methylene Blue
  • LLLT
  • Caffeine – alkaloids in general work by hormesis
  • Ketosis
  • Short-term nutrient deficiency
  • Very low doses of environmental toxins – even heavy metals. The problem is we’re exposed to them chronically often.
  • Getting sick – I don’t recommend it for adults, but kids growing up have a better developed immune system when they play with germs.

Tips for Using Hormesis

  • It’s better to have all the basic building blocks(i.e. proper diet and nutrition) before you start hormetic types of enhancements.
  • The dose is everything.
  • The proper dose can be different for different people in different circumstances.
  • Less is more.
  • Do not “stack”.
  • You must fully heal before taking the next dose.
  • Take breaks. Use different kinds of stressors during these breaks that stress different aspects of the body/mind.
  • Do not use stressors to improve performance during or immediately after. Performance actually takes a dip right after the stimulus. Effects accrue over time, though.
  • When you stop feeling an effect, up the dosage by a little.

Want More Targeted Ways to Enhance Brain Function?

If you’re interested in improving your cognitive function, we recommend checking out SelfDecode’s Limitless Mind DNA Protocol. It gives genetic-based diet, lifestyle and supplement tips that can help improve your cognitive function. The recommendations are personalized based on your genes.

SelfDecode is a sister company of SelfHacked. The proceeds from your purchase of this product are reinvested into our research and development, in order to serve you better. Thanks for your support!

About the Author

Joe Cohen, BS

Joe Cohen won the genetic lottery of bad genes. As a kid, he suffered from inflammation, brain fog, fatigue, digestive problems, anxiety, depression, and other issues that were poorly understood in both conventional and alternative medicine.Frustrated by the lack of good information and tools, Joe decided to embark on a journey of self-experimentation and self-learning to improve his health--something that has since become known as “biohacking”. With thousands of experiments and pubmed articles under his belt, Joe founded SelfHacked, the resource that was missing when he needed it. SelfHacked now gets millions of monthly readers.Joe is a thriving entrepreneur, author and speaker. He is the CEO of SelfHacked, SelfDecode and LabTestAnalyzer.His mission is to help people gain access to the most up-to-date, unbiased, and science-based ways to optimize their health.
Joe has been studying health sciences for 17 years and has read over 30,000 PubMed articles. He's given consultations to over 1000 people who have sought his health advice. After completing the pre-med requirements at university, he founded SelfHacked because he wanted to make a big impact in improving global health. He's written hundreds of science posts, multiple books on improving health, and speaks at various health conferences. He's keen on building a brain-trust of top scientists who will improve the level of accuracy of health content on the web. He's also founded SelfDecode and LabTestAnalyzer, popular genetic and lab software tools to improve health.

Click here to subscribe

RATE THIS ARTICLE

1 Star2 Stars3 Stars4 Stars5 Stars
(5 votes, average: 4.80 out of 5)
Loading...

FDA Compliance

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.