A Review of “Why Isn’t My Brain Working”

I decided to go through “Why Isn’t My Brain Working” after some clients asked me about it and it got good reviews (4.8 stars).


  • While I didn’t glean any “big” new insights, I picked up various small tidbits of information, which was nice.  Overall, it wasn’t a waste of time.
  • He talks about hormones and neurotransmitters and some root causes as to why they may be malfunctioning.
  • He is open-minded and cognitively flexible, which means he doesn’t get fixated on single themes as much as other people.

The BAD:

  • Too much fluff and stories.

He makes rookie mistakes such as:

  • Thinking tiredness after meals comes from insulin resistance.   This is only a small fraction of fatigue.  I explain post-meal fatigue.
  • Talking abut adrenal fatigue too much, which I debunked.
  • Emphasizing leaky gut too much. Leaky gut does play a negative role in health, but it needs to be put in perspective.
  • Thinking that the circadian rhythm is in the hippocampus.   He has a line where he says adrenal issues from chronic stress manifest themselves in the hippocampus as an altered sleep-wake cycle.  This is terribly wrong on all fronts.  The hypothalamus and in particular the SCN is responsible for the altered sleep-wake cycle.  And the adrenals have nothing to do with it.  It’s more like CRH from the paraventricular nucleus causes circadian dysregulation in the Suprachiasmatic nucleus.  Rookie mistake.

It’s unfortunate that alternative health leaders such as Dr. Datis Kharrazian are making these mistakes because he trains other doctors, who are learning the outdated material and will stick with it because they can’t think for themselves and do their own research.

People need to understand that the question shouldn’t be whether someone is right or wrong about a topic.  What matters is the emphasis that is placed on different topics.

For this blog, I’ve emphasized some things too much and other things too little, but as I expand my content, people will get a more balanced picture.

Critical to having a balanced view is to have a panoramic view of the body and treatments.  Only then can you start putting things into perspective.  As I learn more, I shift my emphasis and this will continue to happen.

Health Tools I Wish I Had When I Was Sick

At SelfHacked, it’s our goal to offer our readers all the tools possible to get optimally healthy. When I was struggling with chronic health issues I felt stuck because I didn’t have any tools to help me get better. I had to spend literally thousands of hours trying to read through studies on pubmed to figure out how the body worked and how to fix it.

That’s why I decided to create tools that will help others cut down the guesswork:

  • Lab Test Analyzer – a software tool that will analyze your labs and tell you what the optimal values are for each marker — as well as provide you with actionable tips and personalized health and lifestyle recommendations to help you get there.
  • SelfDecode – a software tool that will help you analyze your genetic data from companies such as 23andme and ancestry. You will learn how your health is being impacted by your genes, and how to use this knowledge to your advantage.
  • SelfHacked Secrets – an ebook where we examine and explain the biggest overlooked environmental factors that cause disease. This ebook is a great place to start your journey if you want to learn the essential steps to optimizing your health.
  • SelfHacked Elimination Diet course – a video course that will help you figure out which diet works best for you
  • Selfhacked Inflammation course – a video course on inflammation and how to bring it down
  • Biohacking insomnia – an ebook on how to get great sleep
  • Lectin Avoidance Cookbook – an e-cookbook for people with food sensitivities
  • BrainGauge – a device that detects subtle brain changes and allows you to test what’s working for you
  • SelfHacked VIP – an area where you can ask me (Joe) questions about health topics

Check out Lab Test Analyzer!

Get personalized up-to-date science-backed lifestyle, diet, and supplement recommendations based on your lab tests!


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