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22 COMMENTS

  • Kacy

    What is the quickest way to boost the alpha levels?

  • Jen

    Hi there , this question may sound ignorant but here goes. I quit smoking 4 years ago, within 4 days of quitting I encountered muscle problems and have lived in a pretty good amount of pain since. I just started researching the good things nicotine can do for you because up until then I was in perfect health and no amount of testing has given me an answer.. Just thought you may have some insight, I am really willing to try anything at this point . Thanks,
    Jennifer

  • Bridget

    Hi, why do you suppose TNFalpha antagonists have been linked to an increased susceptibility to demyelinating disease? Trying to figure that one out.

  • Scloud

    I have low TNF and can’t find any info on this subject. My dr. Believes it could be a cause for my infertility and we are trying to get it up. Have you heard anything like this or have any information on really low TNF? Your article was very interesting.

  • Just Another Russian

    Hey, Joe! You know anything about whether finasteride inhibits TNF-alpha? Thanks.

  • Kanchan Changder

    Amazing n full of knowledge … Many Thanks I have acute AS n I have been suggested Anti TNF Biologics but I want to go with the natural way as its more safe from side effects. What should I include in my diet to block TNF naturally.

  • Luca

    Pentoxifylline! (Trental)

  • にょろ♂

    Amazingly awesome contents !
    BTW, why some are barred on its word in “Top 16 Ways To Inhibit TNF” section ?

  • Jean

    Just got an idea. L-Carnitine Tartrate could possibly yield the same benefits as tamarind (tartaric acid). It’s way cheaper than plain L-carnitine too.

  • Daniel

    Thanks again Joe. I have done some Dna Tests. I have problems with tnf and il 6 and ended up with leaky gut, psoriasis, and ms. Thanks to you I understand more and more about my test results and how to fight my inflamed body.

    1. Joseph M. Cohen

      My pleasure 🙂

  • Jack

    As usual. Top five most effective, based on existing evidence, yet completely safe?

  • Jay

    Have you tried kratom?

    1. Joe

      yup

      1. Jay

        And what were the effects? Good/bad?

        1. Joe

          depends

          1. Jay

            Lol ok don’t give too much away 😉

            reply icon
  • YimYam

    What dosage?

  • Joanna

    Interesting on the MDMA. Might explain why you feel alert and great after 5-6 hours of sleep despite rolling the whole night. The subsequent days seem like less sleep is required as well.

    MDMA is also a selective TH2 and TH1 immunosuppressant. Not sure exactly where I read that but I pulled out a related source anyways.
    http://www.ncbi.nlm.nih.gov/pubmed/10741902

    I would tend to agree with this as my rhinitis and cough completely goes away for a couple days after rolling.

    However, I think you’d run into more problems using MDMA regularly… but interesting none the less.

    Smoking weed semi regularly you can probably get away with without suffering as much adverse effects though.

    Have not tried psychedelics, but the benefits of micro-dosing LSD probably comes from what you mentioned above

    1. Joe

      Lol, you may have seen it here: https://selfhacked.com/blog/supplements-people-th1-dominant/

      I don’t suggest regular MDMA usage.

      Ya microdosing LSD is interesting I plan on trying that too

  • kobilica

    Hello! I am extremely glad you have posted this!

    I can report, that magic mushrooms do indeed have really good potent effect. I feel clearheaded days after the experience (5 days or so, do not remember)

    1. Joe

      Thanks

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