All About Histamine: The Good and The Bad

Histamine is widely known as a substance that contributes to allergies, asthma, eczema, and coughs.

In addition, histamine is also a neurotransmitter with very important roles both in the brain and in the gut. Read this post to learn more about histamine.

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19 Reasons Why High Homocysteine is Bad, and Natural Ways to Decrease It

High homocysteine is linked to many health problems including heart disease, stroke, autoimmune disease, cancer, and neurodegenerative disease.

This post describes:

  • How homocysteine levels can affect your health
  • How homocysteine can be toxic and inflammatory
  • Lab tests for homocysteine levels, with optimal ranges
  • Factors that influence homocysteine levels, including diet, lifestyle, and ways to support the methylation pathways given the relevant genetic information (i.e. MTHFR mutation)
  • How you can optimize your homocysteine levels to improve your performance and wellbeing.

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H. pylori Infection 101: H. pylori Facts and Associated Diseases (Part 1)

It is estimated that more than half of the population is a host for Helicobacter pylori.  While most will show no symptoms, in others this bacterium can lead to chronic stomach inflammation and ulcers. H. pylori infection also exacerbates a number of autoimmune and inflammation-related diseases but may confer protection in other conditions.  Read on to find out when and why H. pylori infection should be treated.

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Negative Health Effects of Artificial Blue Light at Night And What You Can Do About It

Nighttime blue light exposure can derange the circadian rhythm. It is a culprit behind many modern chronic health issues, including obesity, metabolic syndrome, and cancer. On the other hand, blue light exposure during the day is very beneficial. Read this post to learn how to hack your blue light exposure for your benefit.

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Capsaicin

Capsaicin is what makes chili peppers hot. When consumed in a somewhat diluted form, capsaicin has a myriad of health benefits. Some of these include the treatment of nerve disorders and neuropathy, pain relief, and psoriasis treatment. Capsaicin is also known to improve the metabolism.

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Lycopene

Lycopene is a pigment that helps give red fruits and vegetables their color. It has attracted scientific attention due to its effects as a natural antioxidant. Studies have shown that this pigment has potent anti-cancer properties, reduces stress, and helps prevent muscular injury and inflammation.

Introduction

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Lycopene is a common carotenoid found in fruits and vegetables.

Carotenoids are compounds that give fruits and vegetables their red, orange, and/or yellow color.

They are commonly found in tomatoes, apricots, cranberries, grapes, grapefruits, guava, papayas, peaches, and watermelons.

Lycopenes are not essential for humans but are usually incorporated into the diet.

It has antioxidant properties and has claimed anti-cancer properties.

It is often taken as a supplement, but too much lycopene can lead to skin discoloration.

Health Benefits of Lycopene

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1) Lycopene Is an Anti-inflammatory and Protects Against Injury

In rats, lycopene protects from lipopolysaccharide-induced acute lung injury by reducing inflammation (R).

In rodents, it protects from depression-like behaviors and brain cell injury by reducing lipopolysaccharide-induced inflammation (R).

Treatment with lycopene may protect against muscle injury and inflammation in mice (R).

2) Lycopene Prevents Liver Damage

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In rats, lycopene reduced furan- and diabetes-induced toxicity in the rat liver (R).

In ferrets, it reduced tobacco-associated non-alcoholic fatty liver disease and liver cancer (R).

Lycopene treatment improves normal blood levels after being fed a high-fat diet in rats with non-alcoholic fatty liver disease (R).

In male rats, it may reverse hyperhomocysteinemia, a blood disorder, which demonstrates an ability to help protect the liver (R).

3) Lycopene Helps Prevent Stress

Lycopene preserves sperm functionality and prevents sperm mutations caused by oxidative stress due to its antioxidant properties (R).

In mice, it may reduce oxygen deficiency by preventing endoplasmic reticulum stress and relieving any stress-induced cell death (R).

Lactococcus lactis, an important bacteria in dairy products, becomes more resistant to UV stress when combined with lycopene-related genes (R).

When combined with sodium valproate, lycopene reduced seizures and oxidative stress in mice (R).

In rats, daily supplementation of lycopene and gabapentin reversed sensitivity to pain, cold sensitivity, and reduced oxidative stress (R).

4) Lycopene Inhibits Cancer Cell Growth

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In human head and neck squamous cell carcinoma lines, lycopene prevented rapid cell growth and cellular invasion (R).

There is an increase in BCO2 production, a gene that acts as a tumor suppressor in prostate cancer (R).

5) Lycopene May Help Protect the Skin

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In humans, lycopene supplementation protects skin against harmful UV effects (R).

6) Lycopene Reduces Intestinal Damage

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In patients with chronic bacterial prostatitis, a combination of lycopene with other substances such as methylsulfonylmethane extracts improved the efficacy of levofloxacin, an antibiotic (R).

In patients with ulcerative colitis, lycopene reduced fecal blood, mucus, and pus (R).

7) Lycopene Is Neuroprotective

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In rats, lycopene reduced spinal cord injury by promoting the repair of the blood-spinal cord barrier (R).

Lycopene also reduces neuropathic pain by increasing spinal astrocytic connexin 43 gene production (R).

It also reduced learning and memory impairments in rats, and prevented dendritic spine density reduction caused by high-fat diets (R).

8) Lycopene Helps Restore Vitamin A Deficiency

In mice, lycopene supplementation restored vitamin A deficiency (R).

Cons

  • In patients with ulcerative colitis, lycopene did not reduce abdominal pain (R).
  • In an analysis of three studies, lycopene did not prevent prostate cancer as previously claimed and was not associated with colorectal cancer risk (RR2).
  • Lycopene may cause low blood pressure, increase the risk of bleeding, and interfere with estrogen/hormone therapies and chemotherapy medications (R, R2).
  • It may also cause anorexia, chest pain, diarrhea, stomach pressure, gas, indigestion, nausea, skin discoloration, and vomiting (R).

13 Health Benefits of Retinoic Acid Receptors (RARs) Activation – Leaky gut, Autoimmunity, and Metabolism

Optimizing Retinoic Acid Receptors (RARs) function can help you fix leaky gut, lose weight, fix insulin resistance and heal from autoimmune diseases. Read this post to learn about 13 positive and negative effects of RAR activation, and ways to improve them.

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Methylsulfonylmethane (MSM)

Methylsulfonylmethane (MSM) is a naturally occurring sulfur compound stored in every cell of the body. It helps the hair, skin, and nails grow faster, softer and stronger apart from improving neurological functions and reducing pain. Continue to read to know the other benefits of this supplement and why it is essential for you!

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