How to overcome insomnia and optimize your sleep to heal from chronic health problems

If you struggle with fatigue, brain fog, or other inflammatory health problems, it doesn’t matter how many supplements or hacks you use if you can’t fix your sleep.

50% of SelfHacked Clients and from our reader survey suffer from insomnia or poor sleep quality. We find that insomnia has an 80% correlation with brain fog, anxiety, and depression.

Because sleep is so important for healing these health problems, we wrote a book Biohacking Insomnia. It is on sale for $27 for the next 2 weeks. Afterwards, the price will increase to $37.

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All About Histamine: The Good and The Bad

Histamine is widely known as a substance that contributes to allergies, asthma, eczema, and coughs.

In addition, histamine is also a neurotransmitter with very important roles both in the brain and in the gut. Read this post to learn more about histamine.

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Glucocorticoid Receptors: Gateways to Control Your Levels of Stress, Inflammation, and Anxiety

Glucocorticoid receptors are a type of receptors on the outside of our cells that transmit signals from glucocorticoids, such as cortisol. Poor glucocorticoid receptor function due to chronic stress and high CRH can lead to cortisol resistance, which explains why stress can worsen health problems and cause weight gain. Read this post to learn more about glucocorticoid receptors and how to optimize its function.

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Everything You Need to Know about the C-reactive Protein (CRP)

CRP plays an important role in infections. However, this protein is also a marker of low-grade inflammation and a predictor of your cardiovascular disease risk. Find out how this protein links stress, emotional and socioeconomic cues to physiological ones, and how to keep your CRP levels at bay.

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35+ Proven Health Benefits of Vitamin D (Part 1)

Vitamin D is a fat-soluble vitamin that is naturally present in very few foods. It helps fight against cancer, improves physical performance, prevents osteoporosis, helps promote brain function and reduces depression. Deficiency of this vitamin may lead to brain disorders like Parkinson’s and Alzheimer’s.

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Lycopene

Lycopene is a pigment that helps give red fruits and vegetables their color. It has attracted scientific attention due to its effects as a natural antioxidant. Studies have shown that this pigment has potent anti-cancer properties, reduces stress, and helps prevent muscular injury and inflammation.

Introduction

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Lycopene is a common carotenoid found in fruits and vegetables.

Carotenoids are compounds that give fruits and vegetables their red, orange, and/or yellow color.

They are commonly found in tomatoes, apricots, cranberries, grapes, grapefruits, guava, papayas, peaches, and watermelons.

Lycopenes are not essential for humans but are usually incorporated into the diet.

It has antioxidant properties and has claimed anti-cancer properties.

It is often taken as a supplement, but too much lycopene can lead to skin discoloration.

Health Benefits of Lycopene

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1) Lycopene Is an Anti-inflammatory and Protects Against Injury

In rats, lycopene protects from lipopolysaccharide-induced acute lung injury by reducing inflammation (R).

In rodents, it protects from depression-like behaviors and brain cell injury by reducing lipopolysaccharide-induced inflammation (R).

Treatment with lycopene may protect against muscle injury and inflammation in mice (R).

2) Lycopene Prevents Liver Damage

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In rats, lycopene reduced furan- and diabetes-induced toxicity in the rat liver (R).

In ferrets, it reduced tobacco-associated non-alcoholic fatty liver disease and liver cancer (R).

Lycopene treatment improves normal blood levels after being fed a high-fat diet in rats with non-alcoholic fatty liver disease (R).

In male rats, it may reverse hyperhomocysteinemia, a blood disorder, which demonstrates an ability to help protect the liver (R).

3) Lycopene Helps Prevent Stress

Lycopene preserves sperm functionality and prevents sperm mutations caused by oxidative stress due to its antioxidant properties (R).

In mice, it may reduce oxygen deficiency by preventing endoplasmic reticulum stress and relieving any stress-induced cell death (R).

Lactococcus lactis, an important bacteria in dairy products, becomes more resistant to UV stress when combined with lycopene-related genes (R).

When combined with sodium valproate, lycopene reduced seizures and oxidative stress in mice (R).

In rats, daily supplementation of lycopene and gabapentin reversed sensitivity to pain, cold sensitivity, and reduced oxidative stress (R).

4) Lycopene Inhibits Cancer Cell Growth

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In human head and neck squamous cell carcinoma lines, lycopene prevented rapid cell growth and cellular invasion (R).

There is an increase in BCO2 production, a gene that acts as a tumor suppressor in prostate cancer (R).

5) Lycopene May Help Protect the Skin

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In humans, lycopene supplementation protects skin against harmful UV effects (R).

6) Lycopene Reduces Intestinal Damage

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In patients with chronic bacterial prostatitis, a combination of lycopene with other substances such as methylsulfonylmethane extracts improved the efficacy of levofloxacin, an antibiotic (R).

In patients with ulcerative colitis, lycopene reduced fecal blood, mucus, and pus (R).

7) Lycopene Is Neuroprotective

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In rats, lycopene reduced spinal cord injury by promoting the repair of the blood-spinal cord barrier (R).

Lycopene also reduces neuropathic pain by increasing spinal astrocytic connexin 43 gene production (R).

It also reduced learning and memory impairments in rats, and prevented dendritic spine density reduction caused by high-fat diets (R).

8) Lycopene Helps Restore Vitamin A Deficiency

In mice, lycopene supplementation restored vitamin A deficiency (R).

Cons

  • In patients with ulcerative colitis, lycopene did not reduce abdominal pain (R).
  • In an analysis of three studies, lycopene did not prevent prostate cancer as previously claimed and was not associated with colorectal cancer risk (RR2).
  • Lycopene may cause low blood pressure, increase the risk of bleeding, and interfere with estrogen/hormone therapies and chemotherapy medications (R, R2).
  • It may also cause anorexia, chest pain, diarrhea, stomach pressure, gas, indigestion, nausea, skin discoloration, and vomiting (R).

Why Avoiding Sun Will Kill You: 15 Proven Science-Based Health Benefits of Sun

A large number of public health messages over the past century have focused on the dangers of too much sun exposure, such as aging, skin cancer and DNA damage. However, in reality, today’s science tells us that exposure to the ultraviolet radiation (UVR) in sunlight has many beneficial effects on human health.

Indeed, most people are aware of the impact of sun exposure on Vitamin D production, which is a very important factor. However, there is a host of other health benefits that have been overlooked in the debate over how much sun is necessary for optimal health. This article will dive into the science to uncover the various ways in which sun exposure, at the right times and intensities, is a vital component of good health.

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