CYP2D6 is one of the most important detoxication enzymes. CYP2D6 is responsible for the clearance of 20% of clinical drugs, including opioids (codeine, tramadol), antitumor drugs (tamoxifen), antidepressants (fluoxetine), and antipsychotics (haloperidol). In addition, CYP2D6 also metabolizes dopamine and serotonin, and the activity of this enzyme is often associated with human personality, behavior, and disease susceptibility. Read on to find out more about CYP2D6 function, gene variants, and supplements that increase or decrease CYP2D6 activity.
CYP1B1 is an important detoxication enzyme that helps combat oxidative stress. This enzyme is also important for eye development. Mutations in the CYP1B1 gene are associated with congenital glaucoma. On the other hand, lower activity of this enzyme may be protective against obesity and cancer, by regulating the levels of steroid hormones in our bodies. Learn more about this enzyme and factors that can increase or decrease its activity.
Similar to how evolution works in terms of the occurrence of form and function, there can be unique developments leading to the utilization and cultivation of a plant for a use. The Tupi communities and the Guarani people of and around Brazil were the first to utilize and cultivate Illex paraguarinesis (Yerba Mate), a type of Holly, and it is apparently an acquired taste [R].
In this podcast interview, Dr. Gundry exposes the dangerous truth behind lectins and how they relate to inflammation, autoimmune diseases, and obesity. Most importantly, he shares his vast experience and research on why lectins are so harmful to the body, and how to reverse the damages they cause.
Anyone who reads SelfHacked knows I am very ‘anti-lectin’ for people with autoimmune/inflammatory issues. Dr. Gundry, originally a very famous heart surgeon, discovered how dangerous lectins are and altered his career to help people reverse autoimmune disease through his matrix diet. He has completed the only human study related to lectins and is now the most knowledgeable on the subject. His second book “the Plant Paradox” is coming out on April 25th, 2017.
Kombucha is one of my favorite fermented drinks. It gives me energy because of the lactic acid levels. In addition, it contains beneficial yeasts and bacteria, and several other beneficial substances. Read this post to learn more about the science-backed health benefits of kombucha.
Vitamin B7, more commonly known as biotin, is B vitamin. Like all B vitamins, biotin aids the body in breaking down carbohydrates, fats, and proteins for energy production. It also has roles in maintaining healthy skin, hair, and nervous system function.
Read this post to learn more about the many health benefits of biotin.
Nighttime blue light exposure can derange the circadian rhythm. It is a culprit behind many modern chronic health issues, including obesity, metabolic syndrome, and cancer. On the other hand, blue light exposure during the day is very beneficial. Read this post to learn how to hack your blue light exposure for your benefit.