Mean corpuscular hemoglobin (MCH) measures the amount of hemoglobin in your red blood cells. It can be used to help diagnose blood and iron disorders. Keep reading to learn more about the causes and health effects of low and high MCH.
What is Mean Corpuscular Hemoglobin (MCH)?
Mean corpuscular hemoglobin (MCH) is the average amount of hemoglobin in your red blood cells. Hemoglobin is the protein that stores (binds) oxygen, which is what allows your blood to transport oxygen throughout your body. MCH is normally part of a complete blood count, which measures your hemoglobin, hematocrit, and red blood cell count. It can be used to help diagnose anemias and iron disorders [1, 2].
MCH values parallel those of mean corpuscular volume (MCV). This means that when your MCV increase, MCH usually increases as well .
Normal Range of MCH
MCH usually ranges from 27 – 31 pg per cell .
A low mean corpuscular hemoglobin (MCH) means that your red blood cells are smaller than normal (microcytic) .
Microcytosis patients usually do not show any symptoms, unless their anemia is severe. Other blood tests can help determine the cause of microcytosis, such as MCV, RDW, and iron markers .
Causes of Low MCH
1) Iron Deficiency
In a study of 830 subjects, 679 (82%) of the iron deficiency patients also had low MCH .
How to Increase MCH
Eat a healthy and nutritious diet. In order to prevent nutrient deficiency, it is important that your diet contains the recommended amount of iron. If you are iron-deficient, eat more iron-rich foods include liver, meat, fish, eggs, tofu, beans, nuts, seeds, whole grains, and dried fruits [12, 13].
A high mean corpuscular hemoglobin (MCH) means that red blood cells may be bigger than normal (macrocytic) .
By itself, macrocytosis does not cause any symptoms. However, the diagnosis of macrocytosis can help provide information about any underlying health conditions .
Causes of High MCH
1) Megaloblastic Anemia
4) Malaria Infection
Falciparum malaria patients have higher MCH levels than non-infected people .
How to Lower MCH
If you have megaloblastic anemia, you should increase your dietary intake of foods that are rich in vitamin B12 and folate (vitamin B9). Folate can be found in leafy green vegetables, while vitamin B12 is abundant in meat products including chicken, turkey, lamb, beef, and pork liver, and dairy products such as yogurt and milk [22, 23, R].
Reducing your alcohol intake can prevent your MCH from becoming too high. This is because alcohol consumption reduced vitamin B12 levels and can cause megaloblastic anemia, which increases MCH [19, 20, 24].
Irregular MCH Levels?
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