4.2 /5

SelfDecode Review: Upload Your Raw DNA Data and Get a Health Analysis

Written by Victoria Shelton, MS (Social Work) | Last updated:

Overview of SelfDecode

SelfDecode is a DNA analysis site where you can get personalized health suggestions based on your genes. You can upload your raw DNA data from 23andMe, Ancestry, MyHeritage and other sites to find out what your genes have to say about your health.

SelfDecode also offers their own DNA testing kit for health and ancestry analysis if you haven’t already had your genes tested. SelfDecode aims to help people optimize their health and take a data-driven approach to their health regimen.

Most importantly, SelfDecode is the only company utilizing cutting-edge polygenic risk scoring in the direct-to-consumer market. By using artificial intelligence and machine learning, SelfDecode is able to accurately analyze up to 83 million genetic variants from your typical DNA test. This means you will receive the most complete gene-based health analysis and recommendations.

Review of SelfDecode DNA Health Reports

SelfDecode uses polygenic analysis to look at all the relevant genetic variants (up to 1 million+ per report) for a particular health topic and then tells you which diet, supplement and lifestyle choices should work best for you.

Each report provides a comprehensive overview of your genetic predispositions and explains how your genes could be affecting your health.

SelfDecode offers over 500 DNA Health & Trait Reports covering a variety of topics including:

  • Gut Health
  • Mood
  • Sleep
  • Heart Health
  • Joint Health
  • Fatigue
  • Pain
  • Allergies
  • Weight
  • Stress
  • Blood Sugar
  • Anxiety

In this section, we’ll go through SelfDecode’s Brain Summary Report.

At a glance, you will be able to see your risk scores for all the health topics covered by the Brain Summary Report.

You can navigate through the different sections of the report by clicking on the different tabs at the top of the page, including Overview, Details, Recommendations, and Next Steps.

From the Recommendations tab, SelfDecode lists your DNA-based health recommendations in order of priority with the most impactful changes at the top. Additionally, the recommendations take into account all of your genetic variations and health topics covered in the report.

SelfDecode then provides the Impact and Evidence scores for each suggestion, so you can easily see which recommendation is most likely to work best for you.

Example of a recommendation from SelfDecode:

You can easily add recommendations to your regimen directly from your DNA reports. By doing so, you can keep track and edit your recommendations to fit your health routine. SelfDecode allows you to set the frequency and duration for each item.

In the Next Steps section, you can see related Lifestyle Risk Assessments, related lab results and recommended labs, and a custom supplement formula.

Throughout the reports, SelfDecode also provides links to peer-reviewed scientific studies used to generate the reports and recommendations, so you can further explore the science.

SelfDecode Recommendations

In addition to DNA reports, SelfDecode members have access to a database of 20,000 health recommendations. SelfDecode allows users to search for any recommendation, symptom, or health condition in the database to see how it relates to their DNA and lab results.

Review of SelfDecode Lab Analyzer

The lab analyzer tool is designed to help you decipher your lab tests, track your results and get personalized suggestions on how to achieve optimal levels.

Interestingly, SelfDecode doesn’t just tell you what the “normal” ranges are for your lab test results, they explain what the optimal ranges are so that you can know when you need to make changes, even if your doctor said the results were “normal”.

Example of sub-optimal ferritin lab test results:

For each lab marker, SelfDecode gives you an overview of the lab marker in general, provides details regarding the health effects from your lab marker levels and then provides personalized suggestions to raise or lower your levels.

Example of personalized suggestions from the Lab Analyzer tool:

You can input your lab tests very easily by uploading an image or PDF of your lab tests and the lab analyzer tool will automatically pull the information from the document. You will be able to verify and edit the information, or you can always upload your results manually.

You can also purchase labs from SelfDecode, in which case your results will be automatically added to your account.

Review of SelfDecode Ancestry Reports

SelfDecode analyzes over 83 million genetic variants to give users an in-depth ethnicity percentage breakdown, as well as a color-coded map that can help them discover where they’re from.

In addition, SelfDecode’s AI-backed technology allows for the analysis of more data points than other ancestry companies, which provides a more accurate ancestry breakdown.

Users can trace their maternal lineage back through the ages, learning where they started in the world and their journey. You can also learn more about the history and culture that is connected to your DNA through extensive reports that help them get an even better understanding of your roots.

SelfDecode Privacy Policy

Privacy is very important to SelfDecode and they promise to never sell or give away your data. Their comprehensive privacy policy explains that their reason for collecting your information is to provide you with the services you want, like providing gene-based health recommendations.

They employ multiple layers of data protection, including:

  • Secured data encryption
  • HIPAA and GDPR compliant
  • Restricting internal access to any personally identifying information
  • Only collecting the minimum information necessary to provide you with the requested services
  • Payment processing by secure and reputable companies, such as PayPal and Stripe

If you ever want your information removed from their database, all you have to do is submit a request and they will erase all of your information.

SelfDecode Customer Reviews

Reviews of SelfDecode from customers are highly favorable. You can find reviews about SelfDecode on Trustpilot, where they have an excellent trust score.

Some of the main things that customers seem to enjoy about SelfDecode is the fact that it:

  • Is easy to navigate
  • Is more advanced and in-depth than other genetic analysis tools
  • Provides personalized health recommendations based on your genes
  • Is trustworthy and backed by scientific research
  • Helps you improve your health and solve health problems

SelfDecode Review

SelfDecode Review

SelfDecode Review

SelfDecode vs. Other DNA Analysis Tools

When it comes to analyzing your DNA, SelfDecode has some unique features and differences when compared to other DNA testing companies. Some of the differences include:

  • Providing natural supplement, diet and lifestyle suggestions based on your genes that you can implement right away.
  • Explanations regarding why they make each recommendation so that you can understand the science behind the suggestion.
  • Providing a prioritized list of recommendations in each report based on the analysis of all the relevant genes instead of one gene at a time.
  • A Smart Health Recommendation search engine.
  • Taking a holistic approach to give recommendations that are best for your genes AND the health topic.
  • Using AI and machine learning to accurately predict and analyze up to 83 million genetic variants from a typical DNA file.
  • A team of over 60 highly skilled scientists, MDs, PhDs, NDs, and software engineers working to provide the best health information.
  • Supporting all information with peer-reviewed scientific studies in our research and linking to references throughout the text.
  • Checking for contradicting information when providing analysis and recommendations.
  • Never selling your data or giving it away.
  • Providing cutting-edge ancestry analysis.

SelfDecode Review Summary: Is SelfDecode Worth It?

You can upload your DNA to SelfDecode for free to get started. If customers prefer to access the entire platform, they need to sign up for a SelfDecode plan.

SelfDecode operates with a Build Your Own Health Plan model, in which customers can choose to order a DNA kit or upload their DNA data.

Step 1: Subscribe to SelfDecode ($99/year)

Step 2: Analyze your DNA

  • Order a DNA kit ($298)
  • Upload a DNA file ($199)

Step 3: Choose your add-ons (optional)

  • Ancestry DNA reports ($79)
  • 1:1 Consult & Medical Health Reports ($199)

Users who sign up for a SelfDecode plan will receive access to:

  • 500+ DNA health & trait reports
  • Personalized health recommendations based on DNA and labs
  • Personalized meal plan builder
  • Lab analyzer, tracker, and recommendations
  • SNP & gene explorer
  • And more

You will also receive an analysis of up to 83 million genetic variants from your DNA file. You can get more data out of your DNA without having to pay for expensive whole genome sequencing. By analyzing millions of variants, SelfDecode provides you with a complete picture of your health.

Want to try before you commit to a plan? Upload your DNA for free.

About the Author

Victoria Shelton

MS (Social Work)
Victoria is a social worker turned digital marketer with experience in public speaking, professional writing and project management.
She combines her passion for empowering others to make positive life changes with her love of data analysis to provide strategic marketing expertise that prioritizes the customer and allows for data-driven decision making.


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(5 votes, average: 4.20 out of 5)

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