- Introduction to Medium Chain Triglycerides
- Health Benefits of MCTs
- Side Effects
- Technical Section/Mechanisms
- Buy MCT Oil
Introduction to Medium Chain Triglycerides
Medium chain triglycerides (MCTs) have fatty acid tails that are 6-12 carbons in length (R).
There are both synthetic and natural MCTs. Natural sources include coconut oil, palm kernel oil and dairy fat. (R).
There are three main types of MCTs based on their length. Capronic acid has a length of 6 carbons, caprylic acid has a length of 8 carbons, capric acid has a length of 10 carbons, and lauric acid has a length of 12 carbons. The amount of each type varies based on what they are derived from (R).
In the past MCTs have been used in the treatment of digestives problems such as pancreatic insufficiency, fat malabsorption, and severe hyperchylomicronemia (R).
MCT have been considered safe for human consumption by the FDA for over 20 years (R).
Health Benefits of MCTs
In newborn children, MCTs as well as medium chain fatty acids (MCFA) derived from maternal milk, had antimicrobial effects in the gut tract and reduced pathogen transmission (R).
MCTs and MCFAs have also been shown to reduce growth of a certain species of Malassezia, an infectious fungus widespread in hospitals (R).
Studies of MCTs on rats showed improved gut integrity, modulation of the immune response and improved intestinal secretion of antibodies (R).
In piglets MCTs lowered intestinal pH, modulated the gut microenvironment, and potentially prevented post weaning diarrhea (R).
MCTs Aid in Weight Loss
MCTs were found to reduce fat and calorie intake in a study on 36 healthy women (R).
They are broken down faster than LCTs making them more readily used by the body and less likely to be converted to and stored as fat (R).
An analysis of experiments showed after 3 weeks of MCT consumption or more participants had reduced body weight, waist circumference, hip circumference, total body fat, total subcutaneous fat, and visceral fat compared to LCT (R).
Studies performed on cells showed MCTs reduces the conversion of excess carbohydrates to fats (R).
MCTs Enhance Exercise Performance
MCTs Can Affect Cholesterol
Another study done on healthy men reported increases in total cholesterol and LDL cholesterol (R).
MCTs resulted in 12% higher LDL-cholesterol concentrations, 32% higher VLDL-cholesterol concentrations, a 12% higher ratio of LDL to HDL cholesterol, and 22% higher blood total triacylglycerol concentrations (R).
MCTs Helps With Diabetes
MCTs Benefits the Brain
They have also been shown to improve memory compared to placebos in individuals with mild cognitive impairments (R).
One study observed an improvement in cognitive status, especially women, those without diabetes type II, and severe patients (R).
MCTs Improve Muscle Strength for Elderly
MCTs Enhance Effects of Fish Oil
Nausea, stomach cramping and other gut problems are a known side effect of MCTs (R).
A single dose of MCT ranging between 5 and 50 g or a weeklong diet containing 40% MCT-fat systematically leads to elevated post meal oxygen consumption and thermogenesis, increased total fat oxidation, higher energy expenditure and diminished energy storage in comparison with LCT administered under identical conditions (R,R,R).
MCTs are absorbed directly into the portal vein, transported rapidly to the liver for beta-oxidation, and thus increase diet-induced heat creation compared to long-chain triacylglycerols which are absorbed via the intestinal lymphatic ducts and transported by chylomicrons through the thoracic duct into the systemic circulation (R).
- Increases peptide YY and leptin concentrations (R).
- MCT is known to be a good substrate for the conversion of ghrelin to active ghrelin, without necessarily affecting total ghrelin concentrations (R).
- Studies performed on cells showed MCTs induce heat creation and reduces de novo fat production (R).
- MCTs reduce fat mass, through down-regulation of adipogenic genes as well as PPARy (R).
- MCT-supplemented diets constitute a promising tool against adipogenic and steatogenic diseases(R).
- Prevents CD14-activation dependent endotoxemia mediated by LPS (R).
- Increases enzyme activities of the tricarboxylic acid cycle and ketone body utilization in mice (R).
- Antimicrobial effects on C. difficile result from cell membrane disruption (R).
- Suppresses the increase in blood lactate concentration and RPE during moderate-intensity exercise and extends the duration of subsequent high-intensity exercise, at levels higher than those achieved by ingestion of LCT-containing food (R).
- Lowers fat levels in blood and tissues and LDL oxidation by physiological oxidants (R).
- Enhanced glycogen storage and fatty acid synthesis from acetate supplied by enhanced glycolytic flux (R).
- Increased mean fasting blood beta-hydroxybutyrate levels (R).
- Increased C-peptide levels (R).
- Increased amount of blood ketone bodies (R).
- Reduced blood fat peroxides, total cholesterol, triglycerides (TAGs), TNF, IL-6 and C-reactive protein (R).
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