CYP11B2 produces the hormone aldosterone, which helps conserve sodium. Through its effect on sodium, aldosterone can affect blood pressure. Also, when dysfunctional, aldosterone can contribute to the development of heart disease. That is why some CYP11B2 gene variants are associated with elevated blood pressure and heart disease risk. In this post, you will find out more about gene variants and factors that increase or decrease CYP11B2 activity.
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