C60 is still relatively new, but the studies on it showed results so profound that people think they are fraudulent. C60 oil has dramatically increased the life spans of rats and displayed potent antioxidant effects. However, it may also induce DNA mutations. Read on for a breakdown of available science behind C60.

Disclaimer: Clinical studies have yet to determine the effectiveness and safety of C60. We suggest caution if you decide to supplement.

What is C60?

New Antioxidant

Buckminsterfullerene, buckyballs, or C60 is a powerful antioxidant that has effects on unsaturated fats. it removes superoxide, which is a toxic by-product of cellular metabolism that contributes to tissue injury in many human diseases [1].

A review of scientific research has shown the longevity and antioxidant effects of C60 [2].

The proposed mechanism indicates that C60 has the ability to acquire positive charge by absorbing protons; this complex could enter the mitochondria, leading to a decrease in reactive oxygen species production [3].

Computer simulations have shown that C60 has the ability to pass through lipid membranes, enter the cell, and alter its functions [4].

Some C60 derivatives that are produced in the body are water-soluble and apparently non-toxic below concentrations of 1 mg/mL [5].

According to preliminary research, C60 appears to be a potent antioxidant that removes toxic metabolic waste and free radicals.



  • May promote longevity
  • May reduce oxidative stress and inflammation
  • Kills microbes
  • Shields the skin and nerve cells


  • May cause DNA mutations
  • Not studied in humans
  • Long-term safety is unknown

C60 Health Benefits

1) May Promote Longevity

Carboxyl C60 prevented nerve cell death from dehydration or amyloid-beta plaques (cause Alzheimer’s) and allowed mice to live 8 days longer in a 120-day lifetime [6, 7].

Another study found that average lifespan can increase 5-14% even when starting halfway through the lives of mice [8, 9].

The above studies used a derivative of C60 while using the real thing in olive oil (1.7 mg/kg, 2x a month) can produce a 90% increase in rats’ lifespan [10].

C60 prevented nerve damage and greatly increased lifespan in rats and mice.

2) Antioxidant & Anti-inflammatory Properties

An antioxidant like carboxyl prevented age-related decline in mice [11, 12].

Carboxy C60 is significantly better than ubiquinone in preventing fat peroxidation and iron-induced oxidation in cells [12].

Also, malonyl-C60 inhibits nitric oxide synthase, a creator of nitric oxide, in test-tubes [13].

By inhibiting IL-1, matrix metalloproteinases, and TNF-alpha, hydroxyl-C60 prevents inflammation in mice [14].

Water-soluble C60 prevents stress-induced damage and the breakdown of bones. It also prevents the loss of bone cells and bone inflammation in rabbits [15].

In animal and cell studies, C60 prevented age- and stress-related bone loss by fighting inflammation and oxidative damage.

3) Anti-Microbial Properties

When the right kind of photons work with hydroxy C60 it can deactivate mosquito viruses [16].

Also, malonyl C60 killed Group A Streptococcus, which causes strep throat, skin infections, and toxic shock syndrome [17].

4) Neuroprotective Properties

Hydroxyl C60 protects nerves from dying due to overwork in cell cultures [18].

5) Prevents UV Damage

Perfect for incorporating into a skin lotion, C60 Oil stops sunburn in models of human skin [19].

C60 is also able to decrease Th2 and Th17 Dominance, a major contributing factor to many chronic illnesses and autoimmune disorders. Check out SelfHacked Secrets to learn more about your immune dominance and find the advice you need to live a better, healthier life.

In test tubes, C60 was able to kill microbes, protect nerves, and prevent skin UV damage.

C60 Risks

When scientists gave rats much more than we would ever recommend, there were no changes in body fat, protein, sugar, and other molecules [20].

There are stories going around about C60 oil causing DNA damage, but the only study we found on this mentions that corn oil itself was worse than the C60 inside it. It only changed the DNA expression of the lungs and liver [21].

Sister chromatid exchange and micronucleation occur more often from C60 — this can be a source of DNA mutation [22].

C60 oil unwinding DNA could be good or bad. Unwound DNA repairs more easily, as mutated mice missing DNA unwinding enzymes have shorter lives [23, 24, 25].

Even though a study on injecting live mice brains with carboxy fullerene suggested it could be useful in preventing stroke, 20% of the mice that were injected with too much died [26].

Human studies on C60 are lacking, so we don’t know much about its potential side effects and safety profile.

C60 was relatively safe in animal trials. However, it may cause DNA damage. Human safety studies on C60 are lacking.

Buy C60 Oil

C60 Oil is best dissolved in oil with a centrifuge. Pure C60 and high doses of dissolved C60 can be toxic [27].

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Fullerene (buckminsterfullerene or C60) appears to be a potent antioxidant that removes toxic metabolic waste. It can enter the mitochondria and scavenge free radicals.

According to animal and cell-based studies, C60 may promote longevity, reduce oxidative stress and inflammation, protect nerves, and block UV damage. It was relatively safe in animal trials, but it showed the potential to damage DNA.

Fullerene is relatively new and has not yet been studied in humans. At this point, we don’t know much about its health benefits and safety profile.

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