Health Effects of Vitamin B2 (Riboflavin)
Vitamin B2 is effective for riboflavin deficiency, migraine headaches, lowering the risk of developing cataracts and cardiovascular diseases.
What is Vitamin B2?
Vitamin B2, also known as Riboflavin, is a vitamin that plays an integral role in the body as it helps with B6 metabolism and can help combat different disorders.
It plays a vital role in the human body by working with other micronutrients.
Health Benefits of Vitamin B2
Riboflavin significantly reduces the expression of HMGB1 (high-mobility group protein B1), which is one of the factors responsible for inflammation in systemic inflammatory response syndrome (sepsis) in mice (R).
Under various circumstances, it shows anti-inflammatory properties (R).
2) Cognitive Function
Riboflavin is associated with improved cognitive test scores in primary school children in rural Kenya (R).
Higher dietary intake of riboflavin is associated with better abstract performance (R).
Riboflavin treatment in a 16-year-old boy with L-2-hydroxyglutaric aciduria (LHGuria), a rare neurometabolic disorder improved his cognitive function (R).
In many depressed subjects, there was a concurrent Riboflavin deficiency (R).
In elderly, depressed patients, B vitamins (B1, B2, and B6) improved depression (R).
In a Japanese cross-sectional study, increased dietary intake of Riboflavin meant decreased symptoms of depression in girls but not for boys (R).
Consumption of Riboflavin prevents depression after childbirth (R).
4) Eye Health
Increased dietary consumption of Riboflavin leads to a significant decrease in age-related cataracts (R).
Consumption also leads to less age-related opacity in the eyes (R).
5) Cardiovascular Disease
Elderly who had oral Riboflavin supplementation had reduced homocysteine, which causes heart disease (R).
Riboflavin and folate work together to reduce homocysteine levels (R).
Riboflavin consumption (in addition to vitamin B6) reduces colorectal cancer risk in postmenopausal women (R).
7) Bone Health
B2 and other B vitamin play a protective role in bone health (R).
Increased intake of Riboflavin leads to more bone mass density in the neck (R).
8) Liver Health
Riboflavin may be used as a liver-protective agent from liver toxins (R).
Riboflavin also reduces liver injury following liver ischemia and reperfusion in mice (R).
9) Autoimmune Disorders
In a case study, B2 treatment was effective in treating a progressive neurological disorder (Brown–Vialetto–Van Laere syndrome 2) (R).
In mice, B2 helped suppress a motor disability model after the autoimmune disorder, multiple sclerosis (R).
10) Nightly Leg Cramps
B2 (along with other B vitamins) helped reduce the length, pain intensity, and frequency of nocturnal leg cramps in the elderly (R).
In mice, vitamin B2 supplementation leads to more pregnancy, increased weight of the pups, and increased hemoglobin (R).
The recommended allowance of Vitamin B2 is 1.3mg/day for men and 1.1mg/day for women (R).
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The daily recommended dietary allowances (RDAs) of riboflavin (Vitamin B2) are (R):
- Infants 0-6 months, 0.3 mg
- 7-12 months, 0.4 mg
- children 1-3 years, 0.5 mg
- 4-8 years, 0.6 mg
- 9-13 years, 0.9 mg
- men 14 years or older, 1.3 mg
- women 14-18 years, 1 mg
- women over 18 years, 1.1 mg
- pregnant women, 1.4 mg; and breastfeeding women, 1.6 mg.
Vitamin B2 Deficiencies
When iron intake is low, deficiency in B2 may facilitate the development of anemia (R).
Vitamin B2 is a cause of severe allergic reactions (anaphylaxis) (R).
In elderly men with diabetes mellitus, cognitive decline is associated with low intakes of B2 (R).
B2 deficiency is related to a rise in lactate (indicative of a problem in metabolism) (R).
Riboflavin is Likely safe when taken by mouth. In some people, it can cause the urine to turn yellow-orange in color. When taken in high amounts it may cause diarrhea and increased urine (R).
Irregular Vitamin B2 (Riboflavin) Levels?
If you have not yet tested your riboflavin levels, I recommend that you ask your doctor to do it. If you already have your blood test results and you’re not sure what to make of them, you need to check out Lab Test Analyzer. It does all the heavy lifting for you. No need to do thousands of hours of research on what to make of your various blood tests.