Apple Polyphenols have various health benefits. Much of these benefits can be obtained especially when you have your apple with its skin on! Continue reading to know the various health benefits of this dietary polyphenol.

What are Apple Polyphenols?

Polyphenols are organic compounds found in fruits and vegetables. Polyphenols in plants are secondary plant metabolites and can be categorized as flavonoids and non-flavonoids. Apple polyphenols may have beneficial effects on cancer, inflammation, and antioxidation. They are found in the apple itself, but most polyphenols are found in the apple peel.

Health Benefits

1) Anti-Inflammatory Effect

In rats, these polyphenols suppress pro-inflammatory cytokines and improve the antioxidant system [1].

2) Muscular System

In young adult rats, an 8-week diet supplemented with apple polyphenols had improved muscle endurance [2].

In rats, an increased apple polyphenol intake increased muscle endurance and increased fatigue resistance [3].

In rats, polyphenols in apple protected against contraction-induced muscle injuries [4].

3) Cardiovascular System

In rats, polyphenols in apple decreased atherosclerosis and reduced liver inflammation after a 12-week diet [5].

In mice, after chronic cardiac stress, these polyphenols helped decrease electrophysiological disturbances [6].

In human subjects, a supplement of apple juice, containing polyphenols AND vitamin C, mildly improved cardiometabolic markers in comparison to apple polyphenols alone [7].

4) Gut Health

In rats, apple polyphenols had a protective effect against damage caused by aspirin taken on an empty stomach [8].

In rats with colitis, polyphenols in apple improved colon damage [9].

5) Blood Sugar and Weight Management

In rats, polyphenols in apple increased insulin sensitivity, which benefits diabetes management [10].

In rats, polyphenols in apple have anti-obesity effects by regulating genes that produce fat cells [11].

In rats fed with high fat and sucrose diet, those given with apple, cinnamon, and birch polyphenols had lower weight gain and better insulin resistance than those fed without [12].

6) Neuroprotective Effects

In rats, polyphenols in apple had neuroprotective effects against aluminum-caused toxicity [13].

In mice infected with the H1N1 virus, polyphenols in apple reduced stress caused by immune functions and improved recovery and survival rates [14].


Studies done with apple polyphenols are almost exclusively done in animals, so we don’t know what exact benefits it will have in humans.

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