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4 Slippery Elm Benefits + Side Effects, Dosage

Written by Carlos Tello, PhD (Molecular Biology) | Last updated:
Jonathan Ritter
Puya Yazdi
Medically reviewed by
Jonathan Ritter, PharmD, PhD (Pharmacology), Puya Yazdi, MD | Written by Carlos Tello, PhD (Molecular Biology) | Last updated:
Slippery Elm

Native Americans cherished and used the bark of slippery elm for thousands of years in traditional medicine. It was taken to relieve sore throats, stomach and bowel inflammation, to heal wounds, urinary tract infections, and even cancer. Read on to find out if you should be using slippery elm, especially if you have IBS or IBD, and what health benefits are supported by science.

What Is Slippery Elm?

Ulmus rubra, commonly known as slippery elm or moose elm, is a deciduous red tree native to North America and Canada. The tree can grow up to 25 m and its inner bark has a reddish-yellow or reddish-brown color [1].

Slippery elm got its name because its inner bark feels slippery when chewed or mixed with water. The inner bark contains mucilage, a slime-like substance that turns into a gel when it comes in contact with water. Mucilage is a mix of polysaccharides with many medicinal properties [2, 1].

Slippery elm was used by the Native Americans for many purposes, including building canoes and making fire, but also for promoting health. Traditionally, the inner bark of slippery elm has been used as a natural remedy for [1, 3, 4, 5]:

  • Diarrhea
  • Constipation
  • Urinary tract infections
  • Skin injuries and diseases
  • Sore throat & throat infections
  • Stomach and bowel inflammation
  • Cancer

However, these potential health benefits have been insufficiently investigated.

The potential benefits of slippery elm are difficult to fully assess, given the lack of clinical studies. However, limited evidence suggests that slippery elm can help with irritable bowel syndrome (IBS), inflammation, and weight loss [6, 7, 8].

Active Components

The mucilage of slippery elm contains polysaccharides (l-rhamnose, d-galactose, 3-O-methyl-d-galactose, d-galacturonic acid, pectin). After the mucilage comes in contact with water, these polysaccharides break down to sugars (galactose, glucose, and fructose) [9, 10, 11, 12].

The bark of slippery elm also contains [3, 12, 13]:

  • Simple sugars (hexoses, pentoses)
  • Fatty acids (oleic and palmitic acid)
  • Phytochemicals and sterols (oleanolic acid, ursolic acid, beta-carotene, beta-Sitosterol, citrostadienol)
  • Starch
  • Tannins

How Does It Work?

Slippery elm contains mucilage. Mucilage is a substance made from polysaccharides. When mucilage comes in contact with water, it swells up and becomes a gel. This gel has been reported to help soothe dry or inflamed skin, such as in psoriasis. Mucilage can also heal injuries and wounds, soothe a dry throat, and reduce throat inflammation [8, 14, 15, 16].

Slippery elm may help with digestive health problems, since:

  • Mucilage can soothe an inflamed gut, act as a laxative, and relieve constipation [8, 6]
  • Other components can block harmful gut bacteria (such as Citrobacter freundii and Klebsiella pneumoniae) and increase good gut bacteria (such as Bifidobacterium, Lactobacillus, and Bacteroides species) [17, 18].

Slippery elm may fight inflammation and cancer by:

  • Blocking the release of oxygen radicals (superoxide, peroxyl) involved in inflammation, blood vessel damage, DNA damage, and cancer [19, 20, 21, 22].
  • Decreasing the production of interleukin 8 (IL-8), a cytokine that can cause inflammation and cancer [23, 24].

Slippery Elm Health Benefits & Uses

Insufficient Evidence for:

The following purported benefits are only supported by a single clinical trial on a small population. There is insufficient evidence to support the use of slippery elm for any of the below-listed uses. Remember to speak with a doctor before taking slippery elm supplements and never use them as a replacement for approved medical therapies.

1) IBS

Irritable bowel syndrome (IBS) is a chronic disorder that impacts the stomach and intestines. Symptoms include diarrhea or constipation (usually one will be dominant), straining, stomach pains, and bloating [25, 26, 27].

Slippery elm seems to be a better option for people with constipation IBS, as it can increase bowel movements. In people with diarrhea IBS, it may reduce some symptoms but may worsen diarrhea.

Constipation IBS

In a clinical trial on 10 people with constipation IBS, 14 g/day of slippery elm together with other anti-constipation herbs (lactulose, oat bran, and licorice root) for 5 weeks [6]:

  • Increased stool frequency by 20%
  • Improved stool consistency by 29%
  • Reduced straining by 65 %
  • Relieved stomach pain and bloating by ~13%

Diarrhea IBS

In a clinical trial on 21 people with diarrhea IBS, 9 g/day of slippery elm for 5 weeks together with other herbs (dried bilberries, cinnamon, and agrimony) [6]:

  • Reduced straining and stomach pain by ~20%
  • Decreased bloating by 28%
  • Reduced gas and flatulence by 18%.

However, it didn’t help with diarrhea. On the contrary, it increased the frequency of bowel movements by 9%.

2) Sore Throat (Pharyngitis)

Sore throat (pharyngitis) is a common throat infection, usually caused by bacteria or viruses. It causes dryness, scratchiness, throat pain, and difficulty swallowing [28, 29].

Throat Coat is a herbal medicine made from slippery elm, licorice root, and marshmallow root [16].

In a clinical trial with 60 people with a sore throat, Throat coat reduced overall pain and the pain of swallowing faster and better than the placebo [16, 30].

Slippery elm extract killed a microbe typically causing sore throat (Streptococcus pyogenes) and prevented it from forming biofilms [31].

3) Weight Loss and Blood Fat Levels

In 49 healthy people, slippery elm together with antioxidant supplements and a vegan diet decreased weight, total, and LDL cholesterol after 21 days [32].

4) Balancing the Gut Microbiome

In a small trial on 12 healthy people, slippery elm increased gut bacteria that promote a healthy gut microbiome, such as Bifidobacterium, Lactobacillus, and Bacteroides species (which also protect against obesity) [33].

In contrast, it reduced the harmful bacteria that can cause inflammation. These include bacteria that cause [33]:

  • Urinary tract infections (Citrobacter, Pseudocitrobacter, Enterococcus )
  • Urinary tract, respiratory, skin, and stomach infections (Enterobacter)

Case Studies (Very Low to Lacking Evidence)

Despite the traditional use of slippery elm for these conditions in folk medicine, only a few case studies document their improvement with this remedy. Case studies can only be considered anecdotes with a much lower level of evidence than any clinical studies. Proper clinical research is needed to confirm this anecdotal evidence.


Psoriasis is a chronic, inflammatory skin condition that causes red patches and scales over the skin [34].

Since slippery elm contains mucilage, it can soothe dry skin, heal wounds, and could be helpful for people with psoriasis [8, 14].

In 5 people with psoriasis, slippery elm together with saffron tea and a special diet improved all psoriasis symptoms, such as redness, skin thickness, scaling, and the area of the affected skin [15].

Acid Reflux/GERD

Gastroesophageal reflux disease (GERD) is a digestive disorder that causes stomach contents to return back up into the esophagus. Symptoms include heartburn and a sensation of bitter-tasting acid in the throat or mouth (acid regurgitation) [35, 36, 37].

In 3 people with GERD, slippery elm together with other herbs and lifestyle changes (smoking and alcohol cessation) decreased the intensity and frequency of GERD symptoms [38, 39, 40].


Slippery elm together with multivitamins and a magnesium supplement reduced chronic migraines in a 23-year old female with GERD. Slippery elm may have helped more with acid reflux than with migraine, for which magnesium is known to be beneficial [40].

Further research on the benefits of slippery elm for migraines is needed to tease apart the effect.

Animal and Cell Research (Lack of Evidence)

No clinical evidence supports the use of slippery elm for any of the conditions listed in this section. Below is a summary of the existing animal and cell-based research, which should guide further investigational efforts. However, the studies listed should not be interpreted as supportive of any health benefit.

Inflammatory Bowel Disease (IBD)

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder that includes both ulcerative colitis and Crohn’s disease. Both cause diarrhea, weight loss, fatigue and severe stomach pain [41].

How may slippery elm help?

May alter the gut microbiota in IBD

Altered gut microbiota can cause IBD [42].

People with IBD have lower levels of health-promoting Bacteroides bacteria in the gut. Moreover, Lactobacillus spp. and Bifidobacterium spp. are given as probiotics to people with ulcerative colitis or Crohn’s disease [43, 44].

As previously mentioned, slippery elm can fight harmful bacteria that worsen bowel and stomach inflammation, such as Enterobacter, while increasing health-promoting bacteria, such as Bifidobacterium spp., Lactobacillus spp., and Bacteroides spp [33].

May fight inflammation in IBD

Free radicals worsen inflammation and gut damage in IBD [45, 46, 47].

In a cell study, slippery elm blocked the release of oxygen radicals involved in ulcerative colitis [19].


Below, we will discuss some preliminary research on slippery elm’s anticancer activity. It’s mostly in the animal and cell stage and further clinical studies have yet to determine if its compounds are useful in cancer therapies.

Do not under any circumstances attempt to replace conventional cancer therapies with slippery elm or any other supplements. If you want to use it as a supportive measure, talk to your doctor to avoid any unexpected interactions.

In rats with leukemia, slippery elm together with 3 other herbs (burdock root, sheep sorrel, and Chinese rhubarb) restored the number of total white blood cells, lymphatic white blood cells (lymphocytes), and bone marrow white cells (neutrophils) [48].

In cells, this herb mix also decreased the production of immature blood cells and blocked the production of S1P1 (Sphingosine-1-phosphate receptor 1) (S1P1), a protein involved in leukemia [48, 49].

Slippery elm inner bark also decreased the production of interleukin 8 (IL-8), a chemokine that can cause inflammation and cancer in cell-based studies [23, 24].

Essiac is a herbal mixture of slippery elm and burdock root, Indian rhubarb, and sheep sorrel. In cell studies, Essiac blocked the release of free radicals and reduced DNA damage. Essiac also blocked the growth of breast cancer cells. However, a study on over 500 women with breast cancer found this tea ineffective at improving mood and quality of life [50, 51, 52].


In cellular studies, slippery elm blocked the release of free radicals involved in inflammation, DNA damage, and cancer [19, 20, 21, 22].

Slippery elm also blocked the production of interleukin 8 (IL-8), a cytokine that causes inflammation in cells [23, 24].

Slippery Elm For Pets

Slippery elm is a safe herbal supplement that can be given to cats and dogs for digestive problems such as constipation and bowel inflammation.

Slippery elm killed parasites in the stomach and reduced stomach problems, food poisoning, stopped diarrhea and promoted colon health in dogs, cats, and pigs [53].

Slippery elm together with psyllium husks reduced the symptoms of hairballs (vomiting, retching, or coughing) in cats [54].

Limitations and Caveats

Studies about the benefits of the slippery elm are limited and many are reviews rather than clinical trials.

Furthermore, the few clinical trials that were carried out had a small number of participants, and some of their findings are debatable. In most of the clinical studies, slippery elm was only one component of the diet/therapy examined.

Further research on the benefits and side effects of slippery elm is needed.

Side Effects & Precautions

Keep in mind that the safety profile of slippery elm is relatively unknown, given the scarcity of well-designed clinical studies. The list of side effects below is not a definite one, and you should consult your doctor about other potential side effects based on your health condition and possible drug or supplement interactions.

No serious side effects have been reported from taking slippery elm. It is well tolerated but may cause a skin rash or allergy [6, 55].

Pregnant or breastfeeding women should be cautious with slippery elm. Traditionally, it was believed to cause abortions or miscarriages. However, taking slippery elm as a powder or tea is probably not harmful. The risk comes only from using the bark vaginally [56, 57].

Despite the lack of scientific evidence, pregnant women believed that they could trigger an abortion by inserting slippery elm into their cervix. Some cases of slippery elm in the bladders of pregnant women have been documented, although none of them had a miscarriage [56, 57].

Drug Interactions

Supplement/Herb/Nutrient-drug interactions can be dangerous and, in rare cases, even life-threatening. Always consult your doctor before supplementing and let them know about all drugs and supplements you are using or considering.

Slippery elm contains mucilage, which can reduce the absorption of oral drugs and decrease their effectiveness. Therefore, you should take slippery elm at least one hour after taking an oral drug and consult your doctor or pharmacist about possible interactions with your prescription medication [58].


In rats, slippery elm together with other herbs (burdock root, sheep’s sorrel, and Chinese rhubarb) blocked the release of S1P1 (Sphingosine-1-phosphate receptor 1), a protein encoded in the S1P1 gene involved in leukemia [48, 49].

Forms of Supplementation and Dosage

Slippery elm, as an herbal supplement, is available in the form of tea, lozenges, capsules, and powder [4].

Because slippery elm is not approved by the FDA, there is no official dose. The lack of clinical trials implies that there is no proven dose for most conditions either. Additionally, none of the available supplements are standardized.

Despite these limitations, users and supplement manufacturers have established unofficial doses based on trial and error. As a rule of thumb, they consider the following [4]:

  • For gruel: 1.5 – 3 gr of powder in 1 cup (240ml) of water
  • For tea: 4 grams of powder in 2 cups of water
  • For capsules: 200mg – 500mg up to three times a day
  • For lozenges: 1 lozenge daily

User Experiences

The opinions expressed in this section are solely those of slippery elm users, who may or may not have medical or scientific training. Their reviews do not represent the opinions of SelfHacked. SelfHacked does not endorse any specific product, service, or treatment.

Do not consider user experiences as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare providers because of something you have read on SelfHacked. We understand that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider.

Most users were happy with slippery elm. They reported it reduced the symptoms and promoted healing in cases of:

  • Heartburn
  • Irritable bowel syndrome (IBS)
  • Inflammatory bowel disease (IBD)
  • Acid reflux/GERD
  • Diverticulosis
  • Stomach ulcer
  • Sore throat and dry mouth
  • Vaginal yeast infections

There are many supplements widely available but not standardized, so the time it takes for slippery elm to work varies greatly. However, users reported improvements after the first capsule or after the first powder dosage.

However, a few users experienced side effects and health disturbances, such as constipation, diarrhea, and skin allergies.

About the Author

Carlos Tello

Carlos Tello

PhD (Molecular Biology)
Carlos received his PhD and MS from the Universidad de Sevilla.
Carlos spent 9 years in the laboratory investigating mineral transport in plants. He then started working as a freelancer, mainly in science writing, editing, and consulting. Carlos is passionate about learning the mechanisms behind biological processes and communicating science to both academic and non-academic audiences. He strongly believes that scientific literacy is crucial to maintain a healthy lifestyle and avoid falling for scams.


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