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CYP2C8 is one of the most important drug-metabolizing detox enzymes. It processes over 60 clinical drugs including antidiabetics (rosiglitazone), anticancer drugs (paclitaxel, imatinib), and NSAIDs (diclofenac, ibuprofen). Find out how gene variants may affect you in terms of drug response, and which supplements/drugs interfere with CYP2C8 activity.