When I first heard about hydrogen water, scam bells started to go off in my brain.  But then I started to read and realized that hydrogen water has serious potential and some interesting studies.

Hydrogen water contains hydrogen molecules that act as powerful antioxidants. These molecules help neutralize oxygen free radicals that contribute to disease development, inflammation, and aging. Read more to learn about the miraculous benefits of hydrogen water!

Introduction 

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Hydrogen water is loaded with hydrogen molecules that can extinguish free radicals and cross the blood-brain barrier, cell membrane, mitochondria, and even the nucleus.

Because of its unique properties, molecular hydrogen has therapeutic benefits in virtually every organ in the body where it exerts antioxidant, anti-inflammatory, anti-obesity, and anti-allergy actions with no known side effects [R,R2].

Hydrogen Water Snapshot

  • Longevity9/10
  • Inflammation8.5/10
  • Mood7.5/10
  • Cognition8.5/10
  • Energy8/10

Pros

  • Neuroprotective
  • Excellent antioxidant
  • Anti-inflammatory
  • Protects organs
  • Lowers cholesterol and blood sugar
  • Improves a wide variety of diseases
  • Is non-toxic at high concentrations

Cons

  • Although it has no reported side effects, more research is needed for negative effects in the long term

The Health Benefits of Hydrogen Water

1) Hydrogen Water is an Antioxidant and Prevents Brain Damage

Molecular hydrogen (H2) can protect cells and tissues from oxidative damage by selectively reducing reactive oxygen species (ROS) [R,R2].

Unlike other antioxidants, H2 has the unique capability of crossing cell membranes and targeting organelles such as the mitochondria and nucleus [R].

Drinking hydrogen water prevented the development of Parkinson’s disease in an experiment on rats. Hydrogen water reduced oxidative stress and prevented cognitive impairment associated with dementia and Parkinson’s disease [R].

Hydrogen water prevented both the development and progression of neural degeneration, and also suppressed neuronal loss in another Parkinson’s disease mice study [R].

Additionally, in a study on patients with Parkinson’s disease, it was found that the intake of hydrogen water reduces neurotoxic damage, which agrees with previous studies on animals. There were also no adverse effects from the hydrogen water at high doses (1000 mL/day) [R].

2) Hydrogen Water May Improve Mood Disorders

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Hydrogen water restored the natural growth of brain cells in mice. Because antidepressants increase adult neurogenesis, hydrogen water may be used for improving depression and some mental disorders [R,R2].

3) Hydrogen Water Suppresses Inflammation

Molecular hydrogen (H2) exhibits anti-inflammatory effects in many animal studies [R,R2].

In a study, patients with rheumatoid arthritis, a chronic inflammatory disease, drank .5 L/day of hydrogen water for 4 weeks. By the end of the study all patients with early rheumatoid arthritis achieved remission and 20% became symptom-free [R,R2].

4) Hydrogen Water Reduces Muscle Fatigue, Motor Deficits, and Muscle Degeneration

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In an experiment with young athletes, drinking hydrogen water reduced lactic acid build-up during heavy exercise and decreased muscle fatigue [R].

In a study on mice with Duchenne muscular dystrophy (DMD), a devastating muscle disease, hydrogen water prevented abnormal body mass gain and increased the production of the antioxidant glutathione peroxidase. It was found that hydrogen water can potentially improve muscular dystrophy in DMD patients [R].

5) Hydrogen Water Prevents Metabolic Syndrome

Hydrogen water significantly reduced fatty liver in mice with type 2 diabetes and obesity as well as in mice with a highfat-diet-induced fatty liver. Also, levels of glucose, insulin, and triglycerides were decreased by stimulating energy metabolism [R].

A study in rats showed that hydrogen water was able to prevent atherosclerosis (hardening of the arteries) [R].

In a study on patients with the potential for metabolic syndrome, drinking hydrogen water (1.5 – 2 L/day) for 8 weeks showed an increase in HDL-cholesterol (“good” cholesterol) and a decrease in total cholesterol [R].

6) Hydrogen Water May Help in Weight Loss

Long-term drinking of hydrogen water controlled body fat and weight in rats, despite no change in food and water intake [R].

7) Hydrogen Water Enhances Mitochondrial Function

Clinical studies have shown that drinking hydrogen water directly protects the mitochondria and improves the outcome of mitochondrial disorders [R].

Drinking hydrogen water also stimulates energy metabolism (as measured by oxygen consumption and CO2 production) [R].

8) Hydrogen Water Treats Diabetes

A clinical trial in patients with type 2 diabetes and impaired glucose tolerance showed that drinking hydrogen water (900 mL) for 8 weeks decreased cholesterol, normalized glucose tolerance and improved insulin resistance in a majority of the treated patients [R].

9) Hydrogen Water May Treat Metabolic Acidosis

Metabolic acidosis is a condition characterized by an increase in blood acidity, which can be exacerbated with exercise. A study in healthy physically active males found that a daily intake of hydrogen-rich water for 14 days increased the pH of the blood before and after exercise with no side effects. The study concluded that drinking hydrogen water is safe and may have an alkalizing effect in the blood [R].

10) Hydrogen Water May Prevent Cancer

Heated hydrogen water was found to be an effective anti-tumor agent [R].

In human tongue and connective tissue cancer cells, hydrogen water suppressed tumor colony growth by reducing oxidative stress [R].

Hydrogen water also inhibited angiogenesis (blood vessel growth) in cultured human lung cancer cells [R].

11) Hydrogen Water Reduces Side Effects of Cancer Treatments

Drinking hydrogen water improved mortality and body weight loss caused by an anti-cancer drug, cisplatin, and reduced kidney toxicity in mice [R].

In a study on patients receiving radiation therapy for malignant liver tumors, drinking hydrogen water (1.5 – 2 L/day) suppressed oxidative stress (as measured by elevation of total hydroperoxide levels) and prevented the loss of appetite [R].

12) Hydrogen Water Boosts Skin Health

Hydrogen water administered intravenously (into the vein) to patients with acute erythematous skin diseases caused the erythema (redness) and associated symptoms to significantly improve [R].

Bathing in hydrogen water for 3 months significantly improved wrinkles in the skin in a human study [R].

Hydrogen water also reduced human skin cell damage from ultraviolet (UV) rays [R].

13) Hydrogen Water Enhances Would Healing

Hydrogen water intake via tube feeding in elderly patients reduced the wound size of pressure ulcers and enhanced recovery [R].

14) Hydrogen Water Limits Damage of Transplant Organs

Hydrogen water in the form of a preservation solution reduced the damage of a variety of organs during transplantation [R].

15)  Hydrogen Water Improves Bladder Dysfunctions

In a study on rats that were surgically induced with a bladder obstruction, drinking hydrogen water significantly suppressed bladder weight increase and oxidative stress. Also, hydrogen water reversed the decreased responses to muscles and electric field stimulation. These results suggest that hydrogen water could help patients with a bladder obstruction by decreasing oxidative stress [R].

16) Hydrogen Water is Cardio-Protective

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Treating diabetic mice with hydrogen water significantly improved heart muscle function, indicating that molecular hydrogen could be useful for diabetic heart muscle disease [R].

17) Hydrogen Water Protects the Eye

H2-loaded eye drops facilitated the recovery process after retinal injury in rats [R].

Treating the cornea with hydrogen solution significantly reduced angiogenesis (blood vessel growth) after alkali-burn injury in mice, indicating that hydrogen therapy may prevent blindness caused by chemical burns of the eye [R].

18) Hydrogen Water Prevents Hearing Loss

Molecular hydrogen protects auditory hair cells from oxidative damage [R].

Studies in guinea pigs found that hydrogen-rich saline and water prevented the death of cochlear hair cells after noise exposure,  indicating that hydrogen water may protect against noise-induced hearing loss [R,R2,R3].

19) Hydrogen Water Combats Allergy

Drinking hydrogen water eliminated an immediate-type allergic reaction in mice [R].

Atopic dermatitis (AD) is an allergic inflammatory skin disorder characterized by red, scaly rashes on the skin. In mice with AD-like skin, hydrogen water was able to improve symptoms by suppressing inflammation (through manipulation of Th1 and Th2 responses) [R].

20) Hydrogen Water Ameliorates Kidney Disease

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A study in rats found that hydrogen-rich water was able to improve kidney dysfunction from toxic damage by reducing oxidative stress and chemical waste products (creatinine (Cr) and blood urea nitrogen (BUN)) [R].

Drinking hydrogen water also reduced inflammation and blood pressure in hemodialysis patients [R].

21) Hydrogen Water Protects the Liver

Drinking hydrogen water suppressed liver fibrogenesis in mice by protecting liver cells from free-radical damage [R].

Hydrogen water also significantly improved liver function and reduced oxidative stress in patients with chronic hepatitis B [R].

22) Hydrogen Water Promotes Gut Health

Hydrogen-rich water alleviated stomach mucosal injury induced by aspirin in rats (by suppressing oxidative stress and inflammation), indicating that hydrogen water may protect healthy individuals from gut damage caused by oxidative stress [R,R2].

23) Hydrogen Water Protects the Lung

Hydrogen water consumption in rats had a protective effect against lung tissue injury by suppressing inflammation and oxidative stress (through reduction of NF-κB activity) [R].

 24) Hydrogen Water is Radioprotective

A study found that pre-treating mice with hydrogen water before irradiation exposure increased survival rates and protected the heart from radiation-induced damage [R].

Hydrogen treatment also inhibited irradiation-induced death in cultured human white blood cells, suggesting that hydrogen may be used as an effective radioprotective agent [R].

25) Hydrogen Water Relieves Pain

In mice, oral hydrogen water intake was found to alleviate common symptoms of neuropathic pain (allodynia and thermal hyperalgesia). The study concluded that hydrogen water may be helpful for relieving nerve pain in a clinical setting [R].

26) Hydrogen Water May Prolong Lifespan

The ability of molecular hydrogen to protect nuclear DNA and the mitochondria from oxidative damage is thought to have beneficial effects on chronic diseases like cancer and the aging process [R,R2].

H2 treatment delayed the replicative lifespan of bone marrow stem cells by reducing oxidative stress [R].

When human umbilical vein endothelial cells (HUVECs) were grown in a hydrogen-rich medium, both oxidative stress and cellular aging were suppressed. The study concluded that drinking hydrogen water may increase longevity in humans [R].

27) Hydrogen Water is Antibacterial and May Promote Oral Health

A study found that hydrogen water may improve oral hygiene because of its antibacterial effect against cavity and gum disease-causing bacteria [R].

In patients with gum infection, drinking hydrogen-rich water improved disease symptoms and enhanced the effects of non-surgical gum disease treatment [R].

Technical

Safety, Dosage, Side effects, Caution

 Molecular hydrogen (H2) is reported to have no known side effects and is not toxic even at high concentrations [R].

FDA Compliance

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

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39 COMMENTS

  • Nikolay D

    What brand did you buy? Did you perform the test? There may knock offs on the market. $400 machine will not going to last. In a year or two you might start drinking mold and rust from the machine. Be very cautious. I bought my machine for several grands. It lasts 20-25 years. The company is 44 years on the market!! If your machine does’t have 3 types of cleaning, immediately return it to the seller!

  • Gianna

    Can anyone recommend a good hydrogen machine?? Does this help with lymphatic flow? Thanks

  • Skypp

    My first try of hydrogen water was with the tablets, specifically Aquah2 from Amazon. They’re great. I add one more than the directions say: for example 3 tablets in a 23-ounce Perrier bottle, cap tightly, wait 20-30 minutes, drink within a day and keep it tightly capped & cool. Nevertheless, I quickly bought a hydrogen machine and use the tablets when I’m busy or traveling. Some people add a small amount of lime juice when brewing, but no other additives are generally added before it’s made. I am still experimenting, but I love this water and won’t be without it again.

  • Skypp

    You cannot speak to the efficacy of something until you’ve tried it. I bought the tablets just to see. One week later, I was investing in a $400 hydrogen water machine and hope to upgrade that soon. Why? BECAUSE IT’S AWESOME STUFF. I feel better, look better and even wash my face with it. (Immediate glow, freckles diminishing, soft, healthy skin). People who decide something doesn’t work because their “science” tells them so are a special kind of ignorant. MANY very competent scientists are drinking hydrogen water and sharing how to make their own without buying a machine. They seem to think it’s good stuff. Personally, I went for the machine because it was was an easy way to make the water I’ve come to LOVE. Try things for yourselves and don’t ever listen to naysayers, especially ones who have never even tried what they are criticizing.

  • Josh

    So Hydrogen water has PH of WHAT ?

    H2 in solution with NO H+ ions????

    You are telling me Hydrogen water has PH of 7 ?

    this is not alkaline water which is PH above 7 and
    is Hydrogen ion hungery – obviously

    BTW have you guys studied CHI CULITVATION –
    and CHI GONG ? I think you are becoming so BRAIN
    heavy that you might not be grounded !

  • moon

    whether it’s Hydrogen water or regular water one should not over drink like anything else (read that some place, that you can “drown”) — there should be a balance to everything.

  • Alex Tarnava

    You are confusing molecular hydrogen with ionic hydrogen which is a function of pH, and getting that wrong as increasing h+ would lower the pH.

    This is saturating molecular hydrogen, a neutral gas, into water.

    I won’t touch on your latter (incorrect) comment as you don’t even understand the basic premise.

  • Anonymous

    I seriously doubt that hydrolyzed water has any benefit at all(except perhaps a placebo effect benefit). Here’s why:
    When we drink water regardless of its PH it has to go through our digestive track, so by the time the water is absorbed into our bodies it will have its PH changed multiple times. At the final stage its PH will be determined by all our bodies processes to it. More important then, it seems, is the purity of the water and the levels of toxic substances that may be found in it. So apparently the only way to obtain the benefit of the anti-oxidant function of hydrogen would be to inject it, but this could be potentially very dangerous or even fatal.

  • KP Lim

    We have measured the amount of H2 in Izumio and our H2 portable generated water, Izumio is slightly more than the H2 we generated. However, portable generator is much much more economical.

  • Jacqkat

    What’s your opinion on Molecular Hydrogen tablets?

  • K9mom

    What is your opinion on Izumio Hydrogenized Water, any side effects? Can I get sick from drinking too much of it? I have MS & was told it was good for that but not about any possible adverse effects. Thank you & have a Blessed day. 🙂

  • Ed C

    I read several of the studies referenced in the “hydrogen water” section of the the site. I noticed that the studies that showed significant effect often/always(?) generated their water by placing magnesium in water, did nothing to remove the magnesium hydroxide from the water, did not compare result to that obtained from drinking a magnesium hydroxide solution. I am suspicious that all significant effects are due to magnesium and/or hydroxide in the water rather than from dissolved hydrogen.

    Did anyone find any studies which eliminated this possibility?

    Note that some abstracts do not mention the source of their “hydrogen” water so you may have to find the full study text and even then there may not be any mention. In such a case, the study does not tell us whether the dissolved hydrogen has really done anything.

    We are seeking the truth, right?

    1. Alex

      There are hundreds which use different methods. Also hydrogen rich salines, hydrogen inhalation… many use magnesium, and the magnesium intake will have an additive effect, however there are many studies using neutral h2 water via bubbling gas into the water.

      studies on [Molecularhydrogenfoundation] is a good database

  • Shawn Wells

    Aqua magic HE is $99 on Amazon and has the best reviews. It does .8ppm, but can be run a second time to get twice that if needed. It’s portable which is nice. Any thoughts on that one? The two Anself ones have bad reviews. I’d like to get something that works in line with the refrigerator water dispenser too. Does that exist?

    1. Angel

      Dear friends. Greetings to all and of course Joe Cohen!

      My recommendation after buying three (3) different types of equipment is definitely the equipment with SPE (PEM)
      Are expensive but there is nothing better worldwide (I import teams from Japan too)
      This is a summary on the subject very complete
      This is a technical site of disclosure and this is the Spanish site of Japanese equipment with SPE technology but table
      Research and test,
      Angel, Argentine

  • zertu

    hello self hackers, anyone willing to recommenced a product. I’m interested in therapeutic dose H2 (5-7ppm), portable or at home machine. Thanks

    1. Alex Tarnava

      drinkhrw

      tablets, not a machine but they hit those levels

  • Alex

    Molecular hydrogen is showing to be dose dependent. All clinical studies underway and the human studies already published have achieved 4-5 PPM of H2 through a complex system. The only product on the market that can achieve this is Drink HRW’s Rejuvenation drinkhrw.com

    Hydrogen sticks and ionizers tend to get 0.1-0.5 PPM so only a fraction of the required dosage

    Drinkhrw.com has videos demonstrating prep and testing with the methylene blue reagent

    1. Angel

      These videos show the technical measurement of ORP and ppm of hydrogen in water.
      greenfuelh2o.com/H2_Rich_Water_p/h2spe.htm

  • Diarmuid Galvin

    Have you measured the ppm H2 in the water content from the device you have linked to?

    1. Joseph M. Cohen

      No

    2. Alex

      Yes. There are also videos on the site

  • Ali

    I just bought the Anself product you recommended and don’t feel any noticeable effects after 3 days. One review of this product states :

    “Creates lots of pretty H2 bubbles, however, when I tested the water using H2Blue the water stayed blue after the very first drop, proving that the product does not work as claimed.”

    Have you tested the product yourself, or can you recommend another that will definitely produce hydrogen-rich water?

    Thanks for your time and all the effort you put into this site!!

    1. josh

      and the Lourdes one seems to be the best stationary.

      the one recommended on this site is not good enough plus it does NOT separate the water between + and -.

  • Urbane

    Alkaline Water (pH measurement) is missing the point, it is the ORP measurement which matters, it needs to be a negative 3 figure milli-Volts value, but never as negative as -500mv.

    I stopped using water pitcher filters, because construction is noticeable cost cut, the monthly cartridges cost mounts up, they have trivial water capacity, may use potentially harmful plastics (BPA is not the only plasticiser which can be a harmful hormone mimic), and most have poor and/or harmful filtration.

    I have a Big Berkey for the filtration part (excellent filtration/sterilisation, mostly Steel and much cheaper over the years of life of the two huge Black filter sticks, and can have post filters added for nasty stuff like Fluorine and agricultural chemicals) and an Anself Portable Hydrogen Rich Water Ionizer, the resulting water read as -200mv on a brand new, quality ORP meter.

    1. Finalaci

      ORP measurement is also missing the point, since ORP is only the potential. You have to know what made the negative ORP and you also have to know the concentration of it present.

      The concentration of H2 (and thus more/easier availability of therapeutic dosages) is what matters. A low -ORP can easily be orthogonal to what we are after. Water can have a -ORP reading and still have a low concentration of H2.

      It is the PPM (mg/L) that matters. The higher concentration, the more you can take in.

      1. josh

        not to mention somewhere I read the Hydrogen needs to be “active”?
        Found a website somewhere debunking ORP. and said PPM is only guidelines but cant be a perfect element of measure.

  • Nolan

    Picked up the model that was recommended on this past Monday, 8/29/16. Biggest difference I’ve noticed besides a subjective mild anti-inflammatory effect is that my post-meal and fasting blood glucose has stayed somewhat low. During the following readings I was consuming hydrogen water as my primary water source, first meal of day was fat-rich, unless noted otherwise, carbohydrates were concentrated in evening.

    With H2 enriched water:
    91 mg/dL 23:35 8/29 (post meal, carb rich)
    81 mg/dL 10:06 8/30 (low carb morning)
    83 mg/dL 21:36 8/30 (post meal, carb rich)
    84 mg/dL 23:13 8/30 (ate more p.c’d white sweet potatoes)
    77 mg/dL 8:19 8/31
    79 mg/dL 17:34 9/1 (unintentional concomitant intake of carbs following a high fat meal, measured ~1 hr after intake)
    83 mg/dL 10:46 9/2
    91 mg/dL 17:59 9/3 (consumed abundance of carbs , ate a few coconut hi-maize cookies two hours ago)

    Some very recent pre-H2 enriched water samplings of post-carb meal spikes, magnesium adequacy was ensured throughout:

    101 mg/dL 23:01 8/28
    179 mg/dL 19:50 8/28 (ate a rather large serving of sweet potato fries)
    101 mg/dL 23:45 8/25 (post meal, carb rich)
    137 mg/dL 23:59 8/24 (sweet potato fries)
    99 mg/dL 23:59 8/23 (before bed, meal >2 hours prior)

    Very interesting to see that my own objective measurements are corroborating with the research.
    Mood effect is present, although somewhat subtle; probably secondary to reducing pro-inflammatory cytokines.

    1. Joseph M. Cohen

      Nice

  • Markus

    Since it increases endogenous anti-oxidants it’s likely that it works in part as a pro-oxidant.
    If you got your nrf2 epigentically blocked by mycotoxins you can damage yourself very serious.

    http://www.ncbi.nlm.nih.gov/pubmed/18547363

    I have cfs and the hydrogen water oxidized my brain away. Gave me terrible “adrenal fatigue”.
    Got over it by resting, pqq, lllt and sleep.
    I have similar experiences with R-Lipoic Acid, garlic, green tea, gymnostemma, grape seed, etc wich are all strong nrf2 inducers.

    1. lukehastorun

      Use DIM to remove mold toxins from Nrf2…Bacopa also good for mold + nrf2 upregulation.

  • Van Beran

    Seems exciting Joe. Have you honed in on the best way to incorporate its daily use into a household? Which machines are best? Or if the sticks work?

    1. Joseph M. Cohen

      I don’t think stick works

  • GM

    Great article! One question: Are you happy with the product recommended here? (Anself Portable Hydrogen Rich Water Ionizer). Does it really work? Lack of reviews make me a little worried. This stuff looks amazing…

    1. Joseph M. Cohen

      I bought a different, more expensive one, but I were buying now, I’d go for the cheaper linked one. Haven’t tried that one, though.

  • Santino

    Could hydrogen water harm if someone wants to treat chronic infections such as intracellular mycobacteria? For example by attenuating inflammation are being a strong antioxidant?

    1. Joseph M. Cohen

      i don’t think so

  • Astir

    What do you think of this product?
    http://amzn.to/2bDklFX

    1. Ed C

      It doesn’t tell you what minerals are in the “mineral stones” in the filter.

      Why not buy a cost-effective filter and buy beneficial mineral salts to add to your pitcher. You’d know what was dissolved in your water and would not be overpaying for someone to put “stones” in your filter when you really don’t know that they dissolve anything of benefit in the water.

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