- Traditional Medicinal Uses
- The Ashwagandha That I Take
- 1) Ashwagandha is an Anti-Oxidant
- 2) Ashwagandha is an Anti-Inflammatory
- 3) Ashwagandha Combats Anxiety/Stress
- 4) Ashwagandha Enhances Brain Function
- 5) Ashwagandha Induces Fat Cell Death
- 6-10) Ashwagandha Fights Infections
- 11-22) Anti-Cancer Activity of Ashwagandha
- 23-28) Ashwagandha is Neuroprotective
- 29) Ashwagandha Promotes Heart Health
- 30) Ashwagandha is Anti-Diabetic
- 31-32) Ashwagandha Reduces Pain/Fever
- 33-36) Ashwagandha for Women
- 37) Ashwagandha Improves Fertility
- 38) Ashwagandha Reduces Autoimmune Diseases
- 39) Ashwagandha Promotes Bone Health
- 40-44) Hormonal Interactions of Ashwagandha
- 45) Ashwagandha Protects the Liver
- 46) Ashwagandha is Good for the Gut
- 47) Ashwagandha Protects Pancreatic Cells
- 48) Ashwagandha Protects Kidneys
- 49) Ashwagandha Prevents Respiratory Problems
- 50) Ashwagandha for Skin
- 51) Ashwagandha May Reduce Morphine Dependence
- 52) Ashwagandha for Genetic Diseases
- 53) Ashwagandha Helps Muscle Growth
- 54) Ashwagandha For Longevity
- 55) Ashwagandha Prevents Seizures
- 56) Ashwagandha Reduces Age-Related Cataracts
- 57) Ashwagandha Protects Against Industrial Toxins
- 58) Effect of Ashwagandha on Blood Cells
- 59) Ashwagandha is an Effective Anti-Venom
- Ashwagandha Synergies
- Parts Used
- Active Chemical Constituents
- Side Effects
- What Joe Uses
- All Options For Buying Ashwagandha
- Molecular Targets
- Amazon’s Bestsellers
In Sanskrit, Ashwagandha, the Indian name for Withania Sominifera, means “odor of the horse”, probably originating from the odor of its root which resembles that of a sweaty horse (R).
It is also considered an “Adaptogen”, a nontoxic medication that normalizes physiological functions disturbed by chronic stress, through correction of imbalances in the neuroendocrine and immune systems (R).
Although used as a broad spectrum remedy in India for centuries, and mentioned as the “Queen of Ayurveda” Ashwagandha has only recently been under investigation in laboratory settings (R).
Traditional Medicinal Uses
In Ayurveda, the fresh roots are sometimes boiled in milk prior to drying to leach out undesirable constituents (R).
The berries are used as a substitute for Rennet, to coagulate milk in cheese making (R).
A decoction of Ashwagandha root is used as nutrient and health restorative agent among postpartum ladies (R).
Ashwagandha is said to thicken and increase the nutritive value of the breastmilk when given to nursing mothers (R).
The Ashwagandha That I Take
Below, I give a bunch of different good options to buy Ashwagandha, but some people want to to know which one I take.
1) Ashwagandha is an Anti-Oxidant
Ashwagandha (glycowithanolides) is an effective antioxidant (R).
Ashwagandha improved oxidative damage induced by streptozotocin in rats (R).
Chemoprotective activity of Ashwagandha may be due to its antioxidant and detoxifying properties (R).
2) Ashwagandha is an Anti-Inflammatory
Ashwagandha suppressed Myeloid-Derived Suppressor Cells (MDSC) and Tumor-Associated Macrophages (TAMs) (R).
Ashwagandha extract also showed an enhancement in activity of macrophages (R).
3) Ashwagandha Combats Anxiety/Stress
Ashwagandha is specifically used as a tonic to calm the nerves (nervine) (R).
Effects in humans:
Extracts of Ashwagandha may be useful in anxiety disorders for psychiatric practice in humans (R).
Root extract of Ashwagandha at high concentrations safely and effectively improved resistance towards stress and thereby improved self-assessed quality of life in human subjects (R).
Ashwagandha showed a significant decrease in cortisol levels and reduction in stress when compared to placebo (R) (R). Cortisol, the body’s stress hormone, contributes to muscle loss and weakness, wrinkles, and cognitive impairment.
Ashwagandha extract improved auditory-verbal working memory in human subjects with bipolar disorder (R).
Effects in animals:
Ashwagandha extract was effective in treating Obsessive Compulsive Disorder (OCD) in mice (R).
4) Ashwagandha Enhances Brain Function
Ashwagandha belongs to a sub-group of “Rasayanas” (or elixir) known as “Medhyarasayanas” (Medhya refers to the mind and mental/intellectual capacity) (R).
Ashwagandha has a cognition promoting effect. It is useful in children with memory deficit and also prevents memory loss in old age people (R).
Relaxation, a benefit derived from the Ashwagandha’s stress-fighting effects, also improves long-term visual memory (R).
5) Ashwagandha Induces Fat Cell Death
Ashwagandha reduces fat cell viability and synthesis and also induces fat cell death (R).
Ashwagandha root extract can be used for body weight management in adults (R).
Supplementation of Ashwagandha decreased body fat percentage in people (R).
6-10) Ashwagandha Fights Infections
Ashwagandha (Withania sominifera glycoprotein) showed activity against most of the phytopathogenic fungi and bacteria tested (R).
Ashwagandha inhibited fungal growth by inhibiting spore germination and hyphal growth (R).
Ashwagandha showed potent antifungal activity against Aspergillus flavus, Fusarium oxysporum and F. verticilloides (R).
Ashwagandha is widely used to treat Tuberculosis (R).
Ashwagandha showed antibacterial activity against Clvibacter michiganensis subsp. michiganensis (R).
Ashwagandha was active against Staphylococcus aureus (SA) and Methicilin Resistance Staphylococcus aureus (MRSA) (R).
Water extract of Ashwagandha inhibited the growth of gram negative N.gonorrhoea (R).
Oral administration of the water extracts successfully destroyed Salmonella infection in mice (R).
Ashwagandha was found effective in patients with Acute Viral Hepatitis (R).
Water extract of Ashwagandha showed activity against Herpes Simplex Virus Type 1 (HSV-1) cell cultures (R).
Ashwagandha root extract had antiviral property against infectious Bursal Disease virus in cell cultures (R).
Ashwagandha is taken as a suppressant in HIV/AIDS patients (R).
Ashwagandha might be helpful in improving the HIV-1 associated neurocognitive impairments (R).
Ashwagandha is helpful in the treatment of Leishmaniasis (R).
Ashwagandha showed a parasite suppressive effect on rodent malarial parasites (R).
11-22) Anti-Cancer Activity of Ashwagandha
Ashwagandha has potential against cancer-related fatigue, in addition to improving the quality of life (R).
Ashwagandha is a potent and relatively safe radiosensitizer/chemotherapeutic agent (R).
Ashwagandha root extract significantly reduced the rate of cell division in breast tumors (R).
Ashwagandha (Withaferin-A) exhibits activity against colon cancer (inhibits Notch-1) (R).
Alcohol extract of Ashwagandha leaves showed 98% growth inhibition of colon cancer cell lines (HCT-15) (R).
Ashwagandha leaves (Withaferin A, Withanone, Withanolide A) induce growth arrest and differentiation in brain cells and help in treating Glioblastoma (R).
Ashwagandha has anticancer activity against neuroblastoma cells (IMR-32) (R).
Ashwagandha root (Withanolide sulfoxide) inhibits human stomach cancer cell lines (R).
Ashwagandha showed anticancer activity against prostrate cancer cell lines (R).
Ashwagandha (Withaferin A) inhibits tumor Proteosome in human prostrate cancer cell cultures (R).
Ashwagandha is found effective against urethane induced lung-adenoma in mice (R).
Ashwagandha (Withaferin A) exhibited growth inhibition and cytotoxic activity against human lung cancer cell lines (NCI-H460) (R).
Ashwagandha (Withaferin A) inhibited the growth of human kidney cancer cell lines (R).
Ashwagandha was effective in treating human head and neck squamous carcinoma (R).
Long term treatment with Ashwagandha controlled dermatosarcoma (R).
Ashwagandha (Withaferin A) inhibited cancer gene activation and mitochondrial dysfunction in skin epidermal cells (R).
Ashwagandha (Withaferin A) is effective in the treatment and prevention of cervical cancer (R).
Ashwagandha (Withaferin A) decreased the expression of HPV cancer genes, resulting in the death of cervical cancer cells (R).
Alcoholic extract of Ashwagandha root had a protective effect against Dalton’s Ascitic Lymphoma (DAL) (R).
Ashwagandha had anti-tumor effect on Chinese Hamster Ovary (CHO) cell carcinoma (R).
Ashwagandha slows down tumor growth and increases survival time (R).
Ashwagandha stimulates the generation of cytotoxic T lymphocytes, to reduce tumor growth (R).
23-28) Ashwagandha is Neuroprotective
Ashwagandha (metabolites of its constituents) when taken for 7 days, promoted the growth of nerves (R).
Alcohol extract of Ashwagandha promoted the formation of dendrites (R).
Ashwagandha is also useful for neuro-muscular co-ordination (R).
Ashwagandha has potential neuroprotective role for acute stress in rats (R).
Ashwagandha root extract could be useful for the treatment of drug induced dyskinesia (abnormality or impairment of voluntary movement) (R).
Ashwagandha, also showed neurite extension in normal and damaged cortical neurons (R).
Ashwagandha (Alcoholic extract) was effective against scopalamine-induced amnesia in mouse and brain cell culture models (R).
Ashwagandha was found useful in neurodegenerative diseases like Parkinson’s, Huntington’s and Alzeimer’s (R).
There are several studies which show that Ashwagandha slows, stops, reverses or removes neuritic atrophy and synaptic loss (R).
Ashwagandha reversed the behavioral deficits and pathology seen in Alzheimer’s disease models (R).
Orally administered Ashwagandha (Withanoside IV) may improve neuronal dysfunction in Alzheimer’s disease (R).
Ashwagandha significantly reversed ibotenic acid induced cognitive defects in Alzheimer’s disease model (R).
Ashwagandha improves catecholamines, oxidative damage and physiological abnormalities seen in a Parkinson’s disease model mouse (R).
Ashwagandha root extract showed an improvement in the behavioral, anatomical and the biochemical deformities in Parkinsonian mice (R).
Ashwagandha had a neuroprotective effect on the behavioral, biochemical, and mitochondrial dysfunction in an animal model of Huntington’s disease (R).
Ashwagandha was found to be effective for Schizophrenic patients (R).
Attention Deficit-Hyperactivity Disorder (ADHD)
A combination herbal product containing Ashwagandha may improve attention and impulse control in children with ADHD. The effect of Ashwagandha alone is unclear (R).
29) Ashwagandha Promotes Heart Health
Constituents of Ashwagandha are demonstrated to exhibit a favourable “tonic” effect on heart (R).
Ashwagandha treatment found to increase the heart rate, contractility and relaxation (R).
Ashwagandha has been reported to reduce blood pressure (due to automatic ganglion blocking action) (R).
Ashwagandha has a profound activity to reduce cholesterol and prevent hardening of arteries (R).
Ashwagandha has been found to protect the heart in different models of stress and injury
- Ashwagandha improved the cardiorespiratory endurance of elite athletes (R).
- Ashwagandha was protective against oxidative damage in isoproterenol (ISO)-induced heart attack in rats (R).
- Ashwagandha extract provides protection against doxorubicin associated toxicity of heart (R).
- Ashwagandha showed a protective effect in ischemic stroke in rats (R).
- Ashwagandha has been found protective in isoproterenol-induced ischemic rats (R).
- At 50mg/Kg dose, it was found to be the most effective in the functional recovery of the heart in rats (R).
- Supplementation of Ashwagandha with milk is recommended in treatment of stress-oriented hypertension (R).
30) Ashwagandha is Anti-Diabetic
Ashwagandha root was able to induce low blood sugar in humans with type 2 diabetes (R).
Ashwagandha reduced blood glucose levels in alloxan-induced diabetic rats (R).
Ashwagandha improved diabetes-induced testicular dysfunctions in prepubertal rats (R).
Ashwagandha could prevent glycation induced Diabetes (R).
Administration of Ashwagandha for two months could be helpful for the treatment of painful diabetic neuropathy in rats (R).
Ashwagandha had shown strong free radical scavenging activity and helped in improving antioxidant status in type 2 diabetic rats (R).
Withaferin A is partially responsible for Ashwagandha’s anti-diabetic activity (R).
31-32) Ashwagandha Reduces Pain/Fever
Ashwagandha is a pain reliever that soothes the nervous system from pain responses (R).
Ashwagandha (1000 mg/kg/oral) produced significant pain relief for rats experiencing heat induced by hot plate method (R).
Ashwagandha reduce fever as well (R).
33-36) Ashwagandha for Women
Relieves menopausal symptoms
Ashwagandha is effective in the management of menopausal syndrome (R).
It stimulates the hormonal glands and helps regulate the secretion of hormones during menopause (R).
Ashwagandha is also effective in reducing symptoms such as hot flashes, mood fluctuations and anxiety (R).
Ashwagandha root extract stimulates thyroidal activity and also enhances the antiperoxidation of liver tissue (R).
Ashwagandha relaxes the mind and decreases anxiety, thus stabilizing the mood in patients with behavioral disturbances (R), including menopause.
Polycystic Ovary Syndrome (PCOS)
Ashwagandha was one of the components of a polyherbal Ayurvedic preparation called “Testo” (at a concentration of 25 mg) which showed a significant relief in patients with Polycystic Ovary Syndrome (R).
Ashwagandha is best for treating Amenorrhoea (an abnormal absence of mensturation) (R).
Controls Uterine fibroids
Long term treatment with Ashwagandha controlled uterine fibroids (non-cancerous growths that develop in the muscular walls of uterus) (R).
37) Ashwagandha Improves Fertility
Ashwagandha is attributed in Ayurveda for the treatment of oligospermia that causes infertility in male mice (R).
Ashwagandha can balance hormones and improve fertility by promoting relaxation and decreasing stress (R).
Levels of Testesterone (T) were increased in infertile subjects after treatment with Ashwagandha (R).
Ashwagandha improves the functioning of the thyroid gland, which is responsible for regulating reproductive hormones (R).
Ashwagandha is useful for treating Hypogonadism in males (R).
Ashwagandha (Withania somnifera) plant powder for 60 days significantly improved the weights of testes, accessory sex organs in male rats (R).
Ashwagandha is effective in restoration of spermatozoa in mice (R).
Ashwagandha has been found to counteract the formation of ROS (Reactive Oxygen Species) in infertile men (R).
Ashwagandha root extract was effective in increasing sexual competence in male rats (R).
Ashwagandha is also effective on seminal metabolites in infertile males (R).
Ashwagandha is effective in management of psychological-based erectile dysfunction in male patients (R).
38) Ashwagandha Reduces Autoimmune Diseases
Ashwagandha root powder had a preventative effect on the mouse model with Systemic Lupus Erythematosus (SLE) (R).
Ashwagandha root powder reduced inflammation in pristane-induced model of Systemic Lupus Erythematosus (R).
39) Ashwagandha Promotes Bone Health
Ashwagandha stimulates bone formation and is a bone building agent (R).
Ashwagandha had beneficial effects on tibia bone Calcium and Phosphorus content on productive performance of hens without any adverse effects (R).
Leaves of Ashwagandha were effective in preserving bone loss in mice (by both inhibition of resorption and stimulation of new bone formation before onset of osteoporosis) (R).
Ashwagandha root powder had a protective effect on adjuvant-induced arthritis in rats (R).
Ashwagandha improved bone calcification in calcium deficient rats without ovaries (R).
Ashwagandha root powder suppressed gouty arthritis in rats (R).
Water extract of Ashwagandha root powder has chondroprotective effect in osteoarthritis (R).
40-44) Hormonal Interactions of Ashwagandha
Levels of Testesterone (T) were increased in infertile subjects after treatment with Ashwagandha (R).
Follicle Stimulating Hormone
Ashwagandha stimulated the fuction of Thyroid hormone in female mice (R).
Ashwagandha root extract stimulated thyroidal activity in adult male mice (R).
Water extract of Ashwagandha given for 20 days is effective in treating Hypothyroidism (R).
Ashwagandha also prevents Goitre (an enlarged Thyroid) (R).
45) Ashwagandha Protects the Liver
Ashwagandha significantly increases Bile acid content of the liver in rats with high cholesterol (R).
Ashwagandha decreased circulating liver enzymes (Glucose-6-phosphatase), glycogen and restored them to normal levels in alloxan-induced diabetic rats (R).
Ashwagandha prevents ionizing irradiation induced liver toxicity disorders in rats (R).
Ashwagandha is protective to liver in rats against heavy metals (R).
46) Ashwagandha is Good for the Gut
An enema of Ashwagandha water extract is prescribed for intestinal ulcers, irritable bowel and rectal bleeding (R).
Water extracts of Ashwagandha roots restores mucous in rats with Inflammatory Bowel Disease (IBD) (R).
Ashwagandha is used to prevent and treat Hemorrhoids (swollen veins located around the anus or in the lower rectum) (R).
47) Ashwagandha Protects Pancreatic Cells
Ashwagandha (Withaferin A) could be incorporated as a supportive treatment to improve pancreatic transplant outcome (R).
Ashwagandha is protective against pancreatic cell damage in Type 2 diabetic rats (R).
48) Ashwagandha Protects Kidneys
Ashwagandha root extract protects kidney from gentamycin induced toxicity (R).
Ashwagandha was an effective curative for kidney corpuscles from carbendazim-induced damage (R).
49) Ashwagandha Prevents Respiratory Problems
Two teaspoons of Ashwagandha given three times a day helps fast recovery from Bronchitis (R).
50) Ashwagandha for Skin
Ashwagandha (Withaferin A) prevents white spots on the skin (avoids the risk of hypopigmentation of skin) (R).
Ashwagandha root extracts induced skin darkening in wall lizard melanophores (R).
51) Ashwagandha May Reduce Morphine Dependence
Ashwagandha may help reduce dependence on Morphine (R).
Ashwagandha suppressed Morphine withdrawal jumps – a sign of development of dependence to morphine (R).
52) Ashwagandha for Genetic Diseases
Ashwagandha was effective in the treatment of the genetic disease “Congenital Adrenal Hyperplasia” (overgrowth of adrenal gland) in a 57 year-old women (R).
Ashwagandha is also effective in treating symptoms of Down’s Syndrome (R)
53) Ashwagandha Helps Muscle Growth
There was a significant increase in the body weight of rats treated with Ashwagandha when compared to the control (R).
Ashwagandha was effective in treating patients with Sarcopenia (the loss of muscle mass and strength as a result of ageing) (R).
Ashwagandha appeared safe and strengthened muscle activity (R).
54) Ashwagandha For Longevity
Leaf extracts of Ashwagandha (i-Extract) has anti-aging properties (R).
It is also claimed to have potent aphrodisiac rejuvenative and life prolonging properties (R).
55) Ashwagandha Prevents Seizures
Ashwagandha has been used for centuries to control seizures (R).
Ashwagandha is also a component of “Siotone” granules which provide significant protection against pentylenetetrazol-, maximal electroshock- and strychnine-induced convulsions (R).
56) Ashwagandha Reduces Age-Related Cataracts
Ashwagandha was able to retard the formation of cataracts in cells (R).
Ashwagandha plant extract also prevents “diabetic cataracts”, an effect caused due to chronically high blood sugar (R).
Ashwagandha has optimum protective effect against selenite-induced oxidative damage lenses (R).
Ashwagandha is widely used to treat conjunctivitis (R).
57) Ashwagandha Protects Against Industrial Toxins
Ashwagandha leaf extract protects normal human cells against the toxicity of methoxyacetic acid (a major industrial metabolite) (R).
Ashwagandha is also shown to be effective against diesel exhaust, heavy metals and pesticides that harm the various organ systems in the body (R).
58) Effect of Ashwagandha on Blood Cells
Ashwagandha (Withaferin A) triggers suicidal blood cell death (R).
Ashwagandha (leaves) was effective in curing Anaemia prominent in rural women in India (R).
Ashwagandha has the potential to increase red blood cells (R).
Ashwagandha root extract was found to also enhance the total White Blood Cell count (R).
59) Ashwagandha is an Effective Anti-Venom
A glycoprotein purified from Ashwagandha inhibited the hyaluronidase activity of cobra (Naja Naja) and viper (Daboi russelii) venoms (R).
Ashwagandha root in combination with other drugs is prescribed for snake venom as well as for scorpion-sting (R).
Ashwagandha is synergistic with Diazepam in protection against social isolation induced behavior in rats (R).
Ashwagandha along with Anti-tubecular drugs and Chyawanprash (a multi-herbal formulation) were effective in the management of lung Tuberculosis (R).
The Root of Ashwagandha is regarded as a tonic, aphrodisiac, narcotic, diuretic, antiparasitic, astringent, thermogenic and stimulant (R). It is an important ingredient of more than 200 formulations in traditional systems of medicine like Ayurveda, Siddha, and Unani (R).
Leaves are bitter and have a characteristic odor, are recommended for fever and painful swellings (R).
The flowers are astringent, depurative, diuretic and aphrodisiac (R).
Seeds are antiparasitic (R).
In Ayurveda, berries and tender leaves are prescribed to be applied externally to tumors, tubercular glands, carbuncles, and ulcers (R).
Other useful parts are stem, fruits, and bark (R).
Active Chemical Constituents
The biologically active chemical constituents are Alkaloids (isopelletierine, anaferine), Steroidal lactones (Withanolides, Withaferins) (R).
Other components are Saponins (Sitoindoside VII and VIII), and Withanolides (sitoindoside IX and X) (R).
Ashwagandha is also known to structure a wide-range of low molecular weight secondary metabolites like Terpenoids, Flavonoids, Tannins, Phenols, and Resins (R).
The extract of leaves showed the presence of Carbohydrates, Glycosidal sugars, Proteins and Amino acids (R).
It is also a rich source of Iron (R).
A typical dose of Ashwagandha is 3-6 gms daily of the dried root, and 300-500mg of the extract (R).
Maximum benefits appear when fresh Ashwagandha powder is used (R).
Ashwagandha extract was safe when given orally up to 1500mg/kg to rats for 6 months (R).
Hydroalcoholic extract of Ashwagandha at 2000 mg/kg body weight per day had no adverse effects when given to rats and hence may be considered as non-toxic (R).
Ashwagandha is generally safe when taken in the prescribed dosage range (R).
Large doses of Ashwagandha can cause abdominal discomfort and diarrhea (R).
Hyperthyroidism is potentially a serious side effect of Ashwagandha (R).
Ashwgandha use may possibly cause hirsutism (abnormal growth of hair on women’s face) (R).
Ashwagandha is contraindicated during pregnancy since large doses may possess aborting properties (R).
Since Ashwasgandha acts as the mild brain depressant, patients should avoid alcohol, sedative and other anti-anxiety drugs while taking ashwagandha (R).
Since Ashwagandha has the potential to raise thyroid hormone levels, it should not be used by people with hyperthyroidism (R).
EBSCO, an online database, cautions that Ashwagandha is a sedative and it interacts with sedative drugs (R).
What Joe Uses
I normally take 1-2 pills of this Ashwagandha by Paradise Herbs. If you are taking the full spectrum, you need to take a few pills.
All Options For Buying Ashwagandha
Ashwagandha is a very gentle herb, but this also means you likely won’t feel that much with one pill. I personally need to take a few pills to feel relaxing properties.
The reason there are many different products you can purchase is because there are many types of Ashwagandha that are good.
Withanolides are the most active ingredients, so getting those in a good percentage (2.5% or more) can be good.
On the other hand, a full spectrum extract as provided by Paradise Herbs makes sense for the average person.
The best approach is try out different brands and see which you do best with. Everyone is different.
- Ashwagandha by Paradise (AMZN) or Ashwagandha Paradise (IHERB)
- Amazon by Seeking Health – 5% Withanolides (AMZN)
- Ashwagandha (AMZN, General) or Ashwagandha (IHERB, General)
- Ashwagandha 2.5% Withanolides (AMZN)
- Ashwagandha root powder (AMZN)
- Inactivates the TPX2-Aurora A complex (R).
- Inhibits Proteasome (R).
- Decreased the expression of anti-apoptopic proteins Bcl-2 and Bcl-XL (R).
- Inhibits Survivin and Mortalin (R1,R2).
- Inhibits Hsp90 transmission (R).
- Activates Bax/Bak (R).
- Inhibits STAT 3 (R).
- Inhibits Notch-1 (R).
- Inhibits COX-2 enzyme (R).
- Suppresses the increase of acetyl-coA carboxylase-1 (R).
- activates Notch-2, Notch-4
- Inhibits Leishmanial Protein Kinase C (LPKC) (R).
- Decreases p21 (WAF-1) protein (R).
Bone protective activity
- Decreases receptor activator of nuclear factor kappa-B (R).
- Decreases expression of E3 ubiquitin ligase, Smad ubiquitin regulatory factor 2 (Smurf2) (R).
- Increased the expression of CD4 on CD3+ T cells (R).
- Increases expression of IL-2 and IFN-gamma (R).
- Increases IL-7 (R).
- NATURAL STRESS RELIEF - Powerful adaptogen formulation soothes the nervous system, providing a quick, safe, and natural way to relieve stress, anxiety, and insomnia
- THYROID AND HORMONE BALANCE - Our organic herb formula fosters improved thyroid function, and supports reproductive health for men and women
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- ASHWAGANDHA BENEFITS: As a herbal and ayurveda supplement, ashwagandha is continually being researched for new uses. Initial studies suggest it may support vitality, anti anxiety, stress relief, panic attacks and chronic fatigue. This is why many people take it for relaxation, natural calm, alleviating mood swings and depression. Studies also show as an antioxidant, it may have the ability to help strengthen the immune system.
- ONE GREAT PRODUCT, SO MANY NAMES: Winter Cherry, Indian Ginsing, ayush to name a few. Ashwagandha can also be misspelled in many ways, such as: ashwaganda, aswaganda, ashwagandah, ashvagandha, ashawandha, ashwgandha, aswagandha, aswhaganda, ashwagandaha, ashwangda, ashawanda, aschwaganda, aswaghanda, ashwagahnda, ashwgandha, ashwaghanda, aswangandha, ashawangda, ashwagandha himalaya, banyan, brahmi, churna, bocopa, bala and gaia.